Results 171 to 180 of about 966,194 (282)

Bioengineered Extracellular Vesicles Mitigate Neuroinflammation by Neutralizing Pneumolysin and Delaying Disease Onset in Experimental Pneumococcal Meningitis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Bacterial meningitis is a life‐threatening neurological disorder frequently caused by a Streptococcus pneumoniae (the pneumococcus) infection of the brain. Standard treatment consists of antibiotics to eliminate bacteria and dexamethasone to reduce inflammation.
Kristine Farmen   +9 more
wiley   +1 more source

Greater Cochlear Damage in Otogenic Versus Meningogenic Meningitis: Hearing Rehabilitation Implications

open access: yesThe Laryngoscope, Volume 136, Issue 9, Page 3998-4005, September 2026.
Otogenic route of meningitis was associated with greater cochlear hair cell loss in comparison with the meningogenic one in this otopathology study. Neuronal depletion has been traditionally implicated in failed hearing rehabilitation of post‐meningitis deafness.
Matheus Pedrosa Tavares   +5 more
wiley   +1 more source

Effect of the Jeffries Simulation Framework on the Core Competence of New Graduate Paediatric Surgery Nurses: A Quasi‐Experimental Study

open access: yesNursing Open, Volume 13, Issue 9, September 2026.
ABSTRACT Aims Newly graduated paediatric surgery nurses must be able to identify and handle potential risks to ensure patient safety. It is necessary to reinforce their understanding of their roles and responsibilities to achieve this goal. However, the limitations of traditional classroom‐based teaching hinder the exploration of learners' potential ...
Wenjing Luo   +3 more
wiley   +1 more source

Clinical Value of Metagenomic Next‐Generation Sequencing Versus Conventional Methods in Diagnosing Cryptococcal Infection After Kidney Transplantation

open access: yesOrgan Medicine, Volume 3, Issue 3, Page 130-138, September 2026.
This retrospective study evaluated metagenomic next‑generation sequencing (mNGS) against conventional methods (India ink, culture, antigen) for diagnosing cryptococcal infection in 16 kidney transplant recipients. mNGS showed a significantly higher positivity rate (93.8% vs 62.5%, p = 0.031) and shorter turnaround time (24 vs. 120 h, p < 0.001).
Luhao Liu   +6 more
wiley   +1 more source

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf   +10 more
wiley   +1 more source

Fractal–fractional model for analysis of tuberculosis infection using Ethiopia incidence data

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract In this study, a fractional‐order SEIuITR $SE{I}_{u}ITR$ model was proposed to examine the transmission of tuberculosis (TB) in the community. The proposed model was rigorously examined for well‐posedness. The basic reproduction number was also derived, and the disease‐free equilibrium was obtained.
Kumama Regassa Cheneke   +2 more
wiley   +1 more source

Bacterial Meningitis Epidemiology in Burkina Faso and Niger-High-Risk Countries in the Meningitis Belt of Sub-Saharan Africa, 2015-2023. [PDF]

open access: yesJ Infect Dis
Pinell-McNamara VA   +34 more
europepmc   +1 more source

How Do Climatic Factors Directly Influence the Incidence and Risk of Meningococcal Meningitis Across the African Meningitis Belt? A Narrative Literature Review

open access: yesGeoHealth, Volume 10, Issue 9, September 2026.
Abstract Globally, the highest incidence of meningococcal meningitis occurs within the African meningitis belt, spanning 26 countries across sub‐Saharan Africa. Meningococcal meningitis incidence is highly seasonal in this region specifically, with outbreaks mostly occurring during the dry season, characterized by low rainfall and atmospheric humidity,
Molly Cliff   +6 more
wiley   +1 more source

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