Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children [PDF]
, 2014 Extracellular heat shock protein 72 (Hsp72) is an endogenous danger signal and potential biomarker for critical illness in children. We hypothesized that elevated levels of extracellular Hsp72 in the cerebrospinal fluid (CSF) of children with suspected ...
Kernie, Steven G. +5 more
core +1 more source
From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]
, 2017 In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core +3 more sources
Cronobacter, the emergent bacterial pathogen Enterobacter sakazakii comes of age; MLST and whole genome sequence analysis [PDF]
, 2014 Background: Following the association of Cronobacter spp. to several publicized fatal outbreaks in neonatal intensive care units of meningitis and necrotising enterocolitis, the World Health Organization (WHO) in 2004 requested the establishment of a ...
Dickins, B, Forsythe, SJ, Jolley, KA
core +2 more sources
Accepting higher morbidity in exchange for sacrificing fewer animals in studies developing novel infection-control strategies. [PDF]
, 2020 Preventing bacterial infections from becoming the leading cause of death by the year 2050 requires the development of novel, infection-control strategies, building heavily on biomaterials science, including nanotechnology.
Busscher, Henk J. +16 more
core +2 more sources
PLoS ONE, 2021 ObjectivesMeningitis is a medical emergency with permanent disabilities and high mortality worldwide. We aimed to determine causative microorganisms and potential markers for differentiation between bacterial and viral meningitis.MethodologyAdult ...
Sultan F Alnomasy +4 more
doaj +1 more source
Genome analysis of a highly virulent serotype 1 strain of streptococcus pneumoniae from West Africa [PDF]
, 2012 Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and bacteremia, estimated to cause 2 million deaths annually. The majority of pneumococcal mortality occurs in developing countries, with serotype 1 a leading cause in these areas.
Chinelo Ebruke +8 more
core +12 more sources
Impact of a mass vaccination campaign against a meningitis epidemic in a refugee camp. [PDF]
, 1996 Serogroup A meningococcus epidemics occurred in refugee populations in Zaire in August 1994. The paper analyses the public health impact of a mass vaccination campaign implemented in a large refugee camp.
Blok, L +5 more
core +2 more sources
Significant sequelae after bacterial meningitis in Niger: a cohort study [PDF]
, 2013 Beside high mortality, acute bacterial meningitis may lead to a high frequency of neuropsychological sequelae. The Sahelian countries belonging to the meningitis belt experience approximately 50% of the meningitis cases occurring in the world. Studies in
A Hodgson +37 more
core +5 more sources
EBioMedicine, 2019 Background: Historically, the major cause of meningococcal epidemics in the meningitis belt of sub-Saharan Africa has been Neisseria meningitidis serogroup A (NmA), but the incidence has been substantially reduced since the introduction of a serogroup A ...
Nadav Topaz +13 more
doaj +1 more source
The Role of Lactate Dehydrogenase in Differentiating Between Bacterial and Non -Bacterial Meningitis in children Under Five Years in Ramadi Maternity and Children Hospital [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 The present study was designed to find out the usefulness of lactate dehydrogenase (LDH) level in cerebrospinal fluid (CSF) in differentiating bacterial from non-bacterial meningitis in children below 5 year of age .
Adnan M Jasim +2 more
doaj +1 more source