Results 11 to 20 of about 150,001 (350)

The ZNF148-ZEB1-AS1-IGF2BP2-NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis. [PDF]

Glia
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Hu X, Jiang F, Liu X, Li L, Hu R, Dong M, Cao A.   +6 more
europepmc   +2 more sources

Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children [PDF]

, 2014
Extracellular heat shock protein 72 (Hsp72) is an endogenous danger signal and potential biomarker for critical illness in children. We hypothesized that elevated levels of extracellular Hsp72 in the cerebrospinal fluid (CSF) of children with suspected ...
Kernie, Steven G., Lahni, Patrick M., Ma, William, Standage, Stephen W., Wheeler, Derek S., Wong, Hector R.   +5 more
core   +1 more source

From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]

, 2017
In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core   +3 more sources

Molecular characterization of invasive meningococcal isolates in Burkina Faso as the relative importance of serogroups X and W increases, 2008–2012

BMC Infectious Diseases, 2018
Background Neisseria meningitidis serogroup A disease in Burkina Faso has greatly decreased following introduction of a meningococcal A conjugate vaccine in 2010, yet other serogroups continue to pose a risk of life-threatening disease. Capsule switching
Adam C. Retchless, Malika Congo-Ouédraogo, Dinanibè Kambiré, Jeni Vuong, Alex Chen, Fang Hu, Absetou Ky Ba, Abdoul-Salam Ouédraogo, Soumeya Hema-Ouangraoua, Jaymin C. Patel, Rasmata Ouédraogo Traoré, Lassana Sangaré, Xin Wang   +12 more
doaj   +1 more source

Role of Cerebrospinal Fluid Lactate and C-Reactive Protein in Differential Diagnosis of Meningitis in Adults [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Differentiating various types of meningitis is still a challenge as yield of microbiological tests are generally low in these disorders. Aim: To find out the role of Cerebrospinal Fluid (CSF) lactate and CSF C-reactive Protein (CRP) for the
Pediakkal M Jabir, V Valappil Ashraf, Thekkedath Manojan   +2 more
doaj   +1 more source

BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species

BMC Infectious Diseases, 2018
Background Bacterial meningitis is a life-threatening infection that remains a public health concern. Bacterial meningitis is commonly caused by the following species: Neisseria meningitidis, Streptococcus pneumoniae, Listeria monocytogenes, Haemophilus ...
Nadav Topaz, Dave Boxrud, Adam C. Retchless, Megan Nichols, How-Yi Chang, Fang Hu, Xin Wang   +6 more
doaj   +1 more source

Evaluation of IL-8 level in cerebrospinal fluid in acute bacterial meningitis in adults [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز, 2021
Background: Interleukin 8 increases in various types of meningitis, specifically acute bacterial meningitis inflammation, and it is important in the distinction between types of meningitis. The present paper aims at evaluation of the level of interleukin
Zhinous Bayat-Makoo, Puran Karimi, Negar Mohtadi   +2 more
doaj   +1 more source

Microbial aspects and potential markers for differentiation between bacterial and viral meningitis among adult patients.

PLoS ONE, 2021
ObjectivesMeningitis is a medical emergency with permanent disabilities and high mortality worldwide. We aimed to determine causative microorganisms and potential markers for differentiation between bacterial and viral meningitis.MethodologyAdult ...
Sultan F Alnomasy, Bader S Alotaibi, Ahmed H Mujamammi, Elham A Hassan, Mohamed E Ali   +4 more
doaj   +1 more source

Aseptic meningitis in a patient taking etanercept for rheumatoid arthritis: a case report [PDF]

, 2008
Background \ud We report a case of a 53 year old lady recently commenced on etanercept, an anti-TNF (tumour necrosis factor) therapy for rheumatoid arthritis presenting with \ud confusion, pyrexia and an erythematous rash. \ud \ud Case presentation \ud
AP Cairns, B Killingley, DJ Lovell, J Listing, JR Curtis, Julia Flint, M Chávez-López, Matthew J Booker, ME Weinblatt, NR Slifman, P Pagliano, R Quispel, Shanmugam Saravana, WG Dixon   +13 more
core   +4 more sources

Impact of a mass vaccination campaign against a meningitis epidemic in a refugee camp. [PDF]

, 1996
Serogroup A meningococcus epidemics occurred in refugee populations in Zaire in August 1994. The paper analyses the public health impact of a mass vaccination campaign implemented in a large refugee camp.
Blok, L, Boelaert, M, Haelterman, E, Henkens, M, Suetens, C, Toole, M J   +5 more
core   +2 more sources