A prospective study of mortality from cryptococcal meningitis following treatment induction with 1200 mg oral fluconazole in Blantyre, Malawi. [PDF]
OBJECTIVE: We have previously reported high ten-week mortality from cryptococcal meningitis in Malawian adults following treatment-induction with 800 mg oral fluconazole (57% [33/58]).
Allain, TJ +52 more
core +1 more source
Performance of lactate in discriminating bacterial meningitis from enteroviral meningitis
The cytological and biochemical examination of cerebrospinal fluid (CSF) has been used for the presumed diagnosis of bacterial meningitis until the final microbiological results are achieved.
Renan Barros Domingues +3 more
doaj +1 more source
ASSESSMENT OF THE DIAGNOSTIC AND PROGNOSTIC ROLE OF CEREBEROSPINAL FLUID INTERLEUKIN-8 LEVEL IN ADULT PATIENTS WITH MENINGITIS [PDF]
Meningitis necessitates immediate diagnosis and therapy. It is important to distingu- ish bacterial from aseptic meningitis, as this help to avoid complications and unnece- ssary antibiotic use.
LAMIAA ADEL +2 more
doaj +1 more source
Clinical Prediction Rule for Distinguishing Bacterial From Aseptic Meningitis.
New biomarkers like procalcitonin and C-reactive protein may help design an accurate decision support tool used to identify children with pleocytosis at low or high risk of bacterial meningitis.
Fernandez, Catarina Livana +7 more
core +1 more source
A Prospective Longitudinal Study of the Clinical Outcomes from Cryptococcal Meningitis following Treatment Induction with 800 mg Oral Fluconazole in Blantyre, Malawi [PDF]
Introduction: Cryptococcal meningitis is the most common neurological infection in HIV infected patients in Sub Saharan Africa, where gold standard treatment with intravenous amphotericin B and 5 flucytosine is often unavailable or difficult to ...
Mavuto Mukaka +49 more
core +1 more source
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali +4 more
wiley +1 more source
Introduction Haemophilus influenzae is a human-specific Gram-negative bacterium responsible for respiratory tract infection, sepsis, and meningitis. The study aimed to investigate the epidemiology, serotype distribution, and mechanisms of beta-lactam ...
Marlena Kiedrowska +7 more
doaj +1 more source
Diagnosing enterovirus meningitis via blood transcriptomics: an alternative for lumbar puncture?
Background Meningitis can be caused by several viruses and bacteria. Identifying the causative pathogen as quickly as possible is crucial to initiate the most optimal therapy, as acute bacterial meningitis is associated with a significant morbidity and ...
Esther Bartholomeus +24 more
doaj +1 more source
PREDICTING NEUROLOGICAL COMPLICATIONS FOLLOWING ACUTE BACTERIAL MENINGITIS IN CHILDREN VERSUS ADULTS [PDF]
This study determined the predictors for neurological complications of bacterial meningitis in children versus adult patients. This is a prospective study that enrolled 155 Egyptian patients with suspected acute bacterial meningitis (80 children less ...
MOAZ HEIKEL +5 more
doaj +1 more source
Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source

