Results 31 to 40 of about 1,029,387 (219)

Clinical Prediction Rule for Distinguishing Bacterial From Aseptic Meningitis.

, 2020
New biomarkers like procalcitonin and C-reactive protein may help design an accurate decision support tool used to identify children with pleocytosis at low or high risk of bacterial meningitis.
Fernandez, Catarina Livana, Benito, Javier, Mintegi, Santiago, Duran, Isabel, Garcia, Silvia, Martin, Maria Jose, Arana-Arri, Eunate, Hernandez-Bou, Susanna, Susanna Hernández-Bou, Silvia García, Javier Benito, María José Martín, Isabel Durán, Eunate Arana-Arri, Santiago Mintegi, null null, Catarina Livana Fernandez   +16 more
core   +1 more source

ASSESSMENT OF THE DIAGNOSTIC AND PROGNOSTIC ROLE OF CEREBEROSPINAL FLUID INTERLEUKIN-8 LEVEL IN ADULT PATIENTS WITH MENINGITIS [PDF]

Journal of the Egyptian Society of Parasitology, 2016
Meningitis necessitates immediate diagnosis and therapy. It is important to distingu- ish bacterial from aseptic meningitis, as this help to avoid complications and unnece- ssary antibiotic use.
LAMIAA ADEL, FATMA ALI-ELDIN, MUBARAK HUSSIEN   +2 more
doaj   +1 more source

Performance of lactate in discriminating bacterial meningitis from enteroviral meningitis

Revista do Instituto de Medicina Tropical de São Paulo, 2019
The cytological and biochemical examination of cerebrospinal fluid (CSF) has been used for the presumed diagnosis of bacterial meningitis until the final microbiological results are achieved.
Renan Barros Domingues, Gustavo Bruniera Peres Fernandes, Fernando Brunale Vilela de Moura Leite, Carlos Senne   +3 more
doaj   +1 more source

Bacterial meningitis: current therapy and possible future treatment options [PDF]

, 2011
Despite targeted therapy, case-fatality rates and neurologic sequelae of bacterial meningitis remain unacceptably high. The poor outcome is mainly due to secondary systemic and intracranial complications. These complications seem to be both a consequence
Grandgirard, Denis, Uwe Koedel, Klein, Matthias, Stephen Leib, Leib, Stephen, Woehrl, Bianca, Denis Grandgirard, Koedel, Uwe, Bianca Woehrl, Matthias Klein   +9 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Characteristics of Haemophilus influenzae Isolates Responsible for Invasive Infections in Poland in 2018–2023

Infectious Diseases and Therapy
Introduction Haemophilus influenzae is a human-specific Gram-negative bacterium responsible for respiratory tract infection, sepsis, and meningitis. The study aimed to investigate the epidemiology, serotype distribution, and mechanisms of beta-lactam ...
Marlena Kiedrowska, Kinga Błaszczyk, Agnieszka Gołębiewska, Waleria Hryniewicz, Alicja Kuch, Patrycja Ronkiewicz, Izabela Wróbel-Pawelczyk, Anna Skoczyńska   +7 more
doaj   +1 more source

Serum procalcitonin in viral and bacterial meningitis

Journal of Global Infectious Diseases, 2011
Background: In children with meningitis, there is a difficulty to verify the etiology as viral or bacterial. Therefore, intensive research has been carried out to find new and rapid diagnostic methods for differentiating bacterial from viral meningitis ...
Usama M Alkholi, Nermin Abd Al-monem, Ayman A Abd El-Azim, Mohamed H Sultan   +3 more
doaj   +1 more source

PREDICTING NEUROLOGICAL COMPLICATIONS FOLLOWING ACUTE BACTERIAL MENINGITIS IN CHILDREN VERSUS ADULTS [PDF]

Journal of the Egyptian Society of Parasitology, 2019
This study determined the predictors for neurological complications of bacterial meningitis in children versus adult patients. This is a prospective study that enrolled 155 Egyptian patients with suspected acute bacterial meningitis (80 children less ...
MOAZ HEIKEL, DALIA GHORABA, M. FARID, REEM ELMESSIERY, NADIA ABDELKADER, OMAIMA ELHENAWY   +5 more
doaj   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Utility of cerebrospinal fluid cortisol level in acute bacterial meningitis

Annals of Indian Academy of Neurology, 2015
Background: Meningitis remains a serious clinical problem in developing as well as developed countries. Delay in diagnosis and treatment results in significant morbidity and mortality.
Anish Mehta, Rohan R Mahale, Uchil Sudhir, Mahendra Javali, Rangasetty Srinivasa   +4 more
doaj   +1 more source