Results 191 to 200 of about 150,001 (350)

Interaction of Staphylococcus aureus di‐iron Repair of Iron Centers protein with the iron–sulfur cluster assembly SUF system

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract Repair of Iron Centers (RIC) proteins are present in several pathogens, including Staphylococcus aureus, contributing to resistance to nitroxidative stress and virulence. In this work, we investigated the molecular mechanisms by which S. aureus RIC facilitates iron mobilization, through structural analyses and functional studies.
Frederico M. Lourenço   +8 more
wiley   +1 more source

Outcomes of adults with community-acquired bacterial meningitis in the Netherlands: a prospective nationwide cohort study. [PDF]

open access: yesLancet Reg Health Eur
Drost EHGM   +7 more
europepmc   +1 more source

348. Streptococcus agalactiae, Streptococcus pneumoniae, Neisseria meningitidis, and Enterobacateriaceae as Leading Causes of Bacterial Meningitis in Infants Younger than 3 Months Old in a Mexican Hospital: 6 Years of Active Surveillance [PDF]

open access: gold, 2018
Enrique Chacón‐Cruz   +5 more
openalex   +1 more source

Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract High‐temperature requirement A (HtrA) proteases are a conserved family of serine proteases central to protein quality control and bacterial virulence. While Gram‐negative and human HtrAs are structurally well studied, Gram‐positive homologs remain essentially uncharacterized.
Eunjeong Lee   +14 more
wiley   +1 more source

A New Class of Benzo[b]Thiophene‐1,3,4‐Oxadizole Bearing 1,2,4‐Oxadiazoles as Potent Antimicrobial Targets: Synthesis, Biological Evaluation, Docking, DFT and ADMET Studies

open access: yesChemistrySelect, Volume 11, Issue 3, 22 January 2026.
Benzo[b]thiophene‐1,3,4‐oxadizole and 1,2,4‐oxadiazole hybrids 9a–9l were tested against both antibacterial and anticancer, revealing interesting structure‐activity relationships. density functional theory calculations (DFTs) at the B3LYP/6–311++G (d,p).
Ravikumar Gupta Miriyala   +5 more
wiley   +1 more source

Exclusions affect representativeness of Alzheimer's disease trial participants

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract BACKGROUND This study assessed how medical exclusion criteria of a prevention Alzheimer's disease trial impact potential eligibility and sample characteristics. METHODS Medical exclusion criteria from the Anti‐Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial were applied to N = 3695 participants from the population‐based Health
Miriam T. Ashford   +6 more
wiley   +1 more source

Syndrome of Inappropriate Secretion of Antidiuretic Hormone in a Dog With Meningoencephalitis of Unknown Etiology

open access: yesVeterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This report describes a case of syndrome of inappropriate antidiuretic hormone secretion (SIADH) in a Maltese with meningoencephalitis of unknown etiology (MUE). The dog was treated with water restriction and tolvaptan, a vasopressin receptor antagonist, which resulted in an improvement in hyponatremia.
Yelim Lee   +5 more
wiley   +1 more source

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