Results 41 to 50 of about 1,259,375 (319)

The economic burden of RSV-associated illness in children aged < 5 years, South Africa 2011–2016

BMC Medicine, 2023
Background Data on the economic burden of RSV-associated illness will inform decisions on the programmatic implementation of maternal vaccines and monoclonal antibodies.
Jocelyn Moyes, Stefano Tempia, Sibongile Walaza, Meredith L. McMorrow, Florette Treurnicht, Nicole Wolter, Anne von Gottberg, Kathleen Kahn, Adam L. Cohen, Halima Dawood, Ebrahim Variava, Cheryl Cohen   +11 more
doaj   +1 more source

Mathematical Modelling of Bacterial Meningitis Transmission Dynamics with Control Measures

Comput. Math. Methods Medicine, 2018
Vaccination and treatment are the most effective ways of controlling the transmission of most infectious diseases. While vaccination helps susceptible individuals to build either a long-term immunity or short-term immunity, treatment reduces the number ...
Joshua Kiddy K. Asamoah, F. Nyabadza, Baba Seidu, M. Chand, H. Dutta   +4 more
semanticscholar   +1 more source

Diagnosing enterovirus meningitis via blood transcriptomics: an alternative for lumbar puncture?

Journal of Translational Medicine, 2019
Background Meningitis can be caused by several viruses and bacteria. Identifying the causative pathogen as quickly as possible is crucial to initiate the most optimal therapy, as acute bacterial meningitis is associated with a significant morbidity and ...
Esther Bartholomeus, Nicolas De Neuter, Annelies Lemay, Luc Pattyn, David Tuerlinckx, David Weynants, Koen Van Lede, Gerlant van Berlaer, Dominique Bulckaert, Tine Boiy, Ann Vander Auwera, Marc Raes, Dimitri Van der Linden, Helene Verhelst, Susanne Van Steijn, Tijl Jonckheer, Joke Dehoorne, Rik Joos, Hilde Jansens, Arvid Suls, Pierre Van Damme, Kris Laukens, Geert Mortier, Pieter Meysman, Benson Ogunjimi   +24 more
doaj   +1 more source

The value of elevated cerebrospinal fluid lactate concentrations in post-neurosurgical bacterial meningitis

BMC Neurology, 2023
Bacterial meningitis is a serious complication after neurosurgery and has a high mortality rate. Early diagnosis and timely treatment are crucial or will have disastrous consequences.
Qin Wang, YongFang Wang, Yan Yang, YanXi Kong, Yuan Peng   +4 more
doaj   +1 more source

Pediatric Bacterial Meningitis Surveillance in the World Health Organization African Region Using the Invasive Bacterial Vaccine-Preventable Disease Surveillance Network, 2011–2016

Clinical Infectious Diseases, 2019
Background Bacterial meningitis is a major cause of morbidity and mortality in sub-Saharan Africa. We analyzed data from the World Health Organization’s (WHO) Invasive Bacterial Vaccine-preventable Diseases Surveillance Network (2011–2016) to describe ...
J. Mwenda, E. Soda, G. Weldegebriel, R. Katsande, J. Biey, T. Traore, L. De Gouveia, M. du Plessis, A. von Gottberg, M. Antonio, B. Kwambana-Adams, A. Worwui, R. Gierke, Stephanie B. Schwartz, C. V. Van Beneden, A. Cohen, F. Serhan, F. Lessa   +17 more
semanticscholar   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Utility of cerebrospinal fluid cortisol level in acute bacterial meningitis

Annals of Indian Academy of Neurology, 2015
Background: Meningitis remains a serious clinical problem in developing as well as developed countries. Delay in diagnosis and treatment results in significant morbidity and mortality.
Anish Mehta, Rohan R Mahale, Uchil Sudhir, Mahendra Javali, Rangasetty Srinivasa   +4 more
doaj   +1 more source

Risk Factors and Comorbidity in Patients with Bacterial Meningitis

Acta Medica Bulgarica, 2023
Introduction. Bacterial meningitis is a severe disease with high mortality and frequent residual neurological sequelae. It is associated with multiple risk factors.
Argirova P., Kalchev Y., Murdjeva M., Stoycheva M.   +3 more
doaj   +1 more source

Neurological Complications in Young Infants With Acute Bacterial Meningitis

Frontiers in Neurology, 2018
We aimed to evaluate the occurrence, treatment, and outcomes of neurological complications after bacterial meningitis in young infants. A case series study from a retrospective cohort from two tertiary-level medical centers in Taiwan between 2007 and ...
M. Hsu, J. Hsu, H. Kuo, Mei-Yin Lai, M. Chiang, Ying-Jui Lin, Hsuan‐Rong Huang, S. Chu, Ming-Horng Tsai   +8 more
semanticscholar   +1 more source

Succinate Dehydrogenase Subunit A (SDHA) Mediated Microglia Extracellular Traps Formation Participating in Cerebral Ischemic Reperfusion Injury

Advanced Science, EarlyView.
This study investigates the mechanism of succinate dehydrogenase (SDH)‐mediated succinate oxidation in microglia extracellular traps (MiETs) formation and neuronal injury after cerebra I/R injury. Dimethyl malonate (DMM), a competitive SDH inhibitor, could reduce MiETosis by inhibiting succinate oxidation and mtROS production during reperfusion ...
Lili Zhao, Tao Li, Meijuan Dang, Ye Li, Jialiang Lu, Ziwei Lu, Zhiyang Chen, Qiao Huang, Yujie Chen, Yang Yang, Yuxuan Feng, Xiaoya Wang, Yating Jian, Heying Wang, Yingying Guo, Lei Zhang, Yu Jiang, Songhua Fan, Shengxi Wu, Hong Fan, Fang Kuang, Guilian Zhang   +21 more
wiley   +1 more source