Results 51 to 60 of about 1,259,375 (319)

Serum procalcitonin in viral and bacterial meningitis

Journal of Global Infectious Diseases, 2011
Background: In children with meningitis, there is a difficulty to verify the etiology as viral or bacterial. Therefore, intensive research has been carried out to find new and rapid diagnostic methods for differentiating bacterial from viral meningitis ...
Usama M Alkholi, Nermin Abd Al-monem, Ayman A Abd El-Azim, Mohamed H Sultan   +3 more
doaj   +1 more source

Loop-Mediated Isothermal Amplification Methods for Diagnosis of Bacterial Meningitis

Frontiers in Pediatrics, 2018
The rapid, accurate, and efficient identification of an infectious disease is critical to ensure timely clinical treatment and prevention in public health settings.
M. Seki, P. Kilgore, E. J. Kim, M. Ohnishi, S. Hayakawa, D. W. Kim   +5 more
semanticscholar   +1 more source

Clinical Prediction Rule for Distinguishing Bacterial From Aseptic Meningitis

Pediatrics, 2020
This is a multicenter study in which we designed a clinical prediction rule to distinguish children with bacterial and aseptic meningitis. BrightcoveDefaultPlayer10.1542/6166449008001PEDS-VA_2020-1126 Video Abstract BACKGROUND: New biomarkers like ...
S. Mintegi, Silvia García, María José Rivero Martín, I. Durán, E. Arana-Arri, C. Fernandez, J. Benito, S. Hernández-Bou   +7 more
semanticscholar   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

Burden of bacterial meningitis in India: Preliminary data from a hospital based sentinel surveillance network

PLoS ONE, 2018
Background Worldwide, acute bacterial meningitis is a major cause of high morbidity and mortality among under five children, particularly in settings where vaccination for H. influenzae type b, S. pneumoniae and N. meningitidis is yet to be introduced in
Y. Jayaraman, B. Veeraraghavan, G. K. Chethrapilly Purushothaman, B. Sukumar, B. Kangusamy, Ambujam Nair Kapoor, N. Gupta, S. Mehendale   +7 more
semanticscholar   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, EarlyView.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

A Diagnostic Formula for Discrimination of Tuberculous and Bacterial Meningitis Using Clinical and Laboratory Features

Frontiers in Cellular and Infection Microbiology, 2020
Background: The discrimination of tuberculous meningitis and bacterial meningitis remains difficult at present, even with the introduction of advanced diagnostic tools.
Yun Yang, Xin-Hui Qu, Kun-Nan Zhang, Xiao-Mu Wu, Xin-Rong Wang, An Wen, Ling-Juan Li   +6 more
doaj   +1 more source

Frequency of etiological agents of acute bacterial meningitis using culture and polymerase chain reaction assay

New Microbes and New Infections, 2021
Bacterial meningitis is one of the most severe infectious diseases with high rate of morbidity and mortality in developing countries. The current study aimed to investigate the frequency of etiological agents of bacterial meningitis among patients ...
H. Zeighami, S. Roudashti, Sh. Bahari, F. Haghi, N. Hesami   +4 more
doaj   +1 more source

Bacterial meningitis and tuberculous meningitis. [PDF]

BMJ, 1973
Despite the wide range of antimicrobial drugs available to day the mortality and morbidity from bacterial meningitis is disappointingly high. This disappointment is all the more poignant when one appreciates that some 75% of pyogenic meningitis in Britain results from infection by one of three organisms?namely, Neisseria meningitidis, Streptococcus ...
openaire   +3 more sources

Narsoplimab Results in Excellent Survival in Adults and Children With Hematopoietic Cell Transplant Associated Thrombotic Microangiopathy (TA‐TMA)

American Journal of Hematology, EarlyView.
ABSTRACT Inappropriate complement activation is a key driver of hematopoietic cell transplant‐associated thrombotic microangiopathy (TA‐TMA). Treatment with narsoplimab, an inhibitor of MASP‐2, the effector enzyme of the lectin pathway, resulted in a response rate of 61% in a Phase 2 clinical trial in adults with TA‐TMA.
Michelle L. Schoettler, Sunil Kumar Pusarla, Narinder Nangia, Miguel‐Angel Perales, Rafael F. Duarte, Andreas Grauer, Alessandro Rambaldi   +6 more
wiley   +1 more source