Results 91 to 100 of about 1,608,280 (314)

Experiment on bacterial resistance: Bacterial twitching motility on vibrio strains

, 2017
Experiment on bacterial resistance: Bacterial twitching motility on vibrio ...
Piecyk, Agnes, Liesegang, Heiko, Hertel, Robert, Olivia Roth (6979883), Carolin Charlotte Wendling (6979874), Dominik Refardt (8019098), Cynthia Chipani (6979877), Bunk, Boyke, Agnes Piecyk (8019095), Boyke Bunk (8019101), Refardt, Dominik, Robert Hertel (712769), Roth, Olivia, Chipani, Cynthia, Heiko Liesegang (6979880), Wendling, Carolin Charlotte, Jörg Overmann (140902), Overmann, Jörg   +17 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Biophysical investigation of bacterial aggregation [PDF]

, 2008
In nature, bacteria usually exist as aggregates, in order to withstand changes in environmental conditions. Bacterial aggregation is of great significance in the field of biotechnology, environmental studies and medicine.
Eboigbodin, Kevin Efosa
core  

Correlation between Protection against Sepsis by Probiotic Therapy and Stimulation of a Novel Bacterial Phylotype

, 2011
Item does not contain fulltextProphylactic probiotic therapy has shown beneficial effects in an experimental rat model for acute pancreatitis on the health status of the animals.
Smidt, H., Gooszen, H.G., Rijkers, G.T., Minnen, L.P. van, van Minnen, L.P., Fuentes, S., Akkermans, L.M., Hauke Smidt, Minnen, L.P., van, Frans M. Rombouts, Gerritsen, J., Ger T. Rijkers, Susana Fuentes, Jacoline Gerritsen, Konstantinov, S.R., Akkermans, L.M.A., Rombouts, F.M., Panneman, H., Harro M. Timmerman, Henk Panneman, Louis M. A. Akkermans, L. Paul van Minnen, Hein G. Gooszen, Timmerman, H.M., Sergey R. Konstantinov   +24 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Differential Dynamic Microscopy of Bacterial Motility

Physical Review Letters, 2011
4 pages, 4 figures. In this updated version we have added simulations to support our interpretation, and changed the model for the swimming speed probability distribution from log-normal to a Schulz distribution.
Wilson, Laurence G., Martinez, Vincent A., Schwarz-Linek, Jana, Tailleur, J., Pusey, Peter N., Bryant, Gary, Poon, Wilson C. K.   +6 more
openaire   +4 more sources

Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle [PDF]

, 2013
Many bacteria mediate important life-style decisions by varying levels of the second messenger c-di-GMP. Behavioral transitions result from the coordination of complex cellular processes such as motility, surface adherence or the production of virulence ...
Abel, Sören, Bucher, Tabitha, Isabelle Hug (251572), Urs Jenal (37942), Isabelle Hug, Volkhard Kaever, Tabitha Bucher, Pia Abel zur Wiesch (353268), Jenal, U., Sören Abel, Bucher, T., Pia Abel Zur Wiesch, Micaël Nicollier, Micaël Nicollier (454806), Urs Jenal, Volkhard Kaever (152216), Hug, Isabelle, Tabitha Bucher (454805), Sören Abel (454804), Abel Zur Wiesch, P., Kaever, Volkhard, Hug, I., Abel zur Wiesch, Pia, Nicollier, M., Nicollier, Micaël, Abel, S., Jenal, Urs, Kaever, V.   +27 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Ecological relevance of flagellar motility in soil bacterial communities

Flagellar motility is a key bacterial trait as it allows bacteria to navigate their immediate surroundings. Not all bacteria are capable of flagellar motility, and the distribution of this trait, its ecological associations, and the life history ...
Strickland, Michael S, Ramoneda, Josep, Fierer, Noah, Bissett, Andrew, Fan, Kunkun, Strickland, Michael S., Lucas, Jane M., Chu, Haiyan   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source