Results 151 to 160 of about 258,018 (275)

Preparation of Bacterial Outer Membrane Vesicles for Characterisation of Periplasmic Proteins in Their Native Environment

, 2020
Johannes Thoma, Björn M. Burmann
openalex   +2 more sources

Drug Delivery Technologies for the Treatment of Age‐Related Macular Degeneration

Advanced Science, EarlyView.
There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
J Jesus Rodriguez‐Cruz, Jessica Cutrufello, Michael Lam, Shreya Nallaparaju, Nicholas A. Peppas   +4 more
wiley   +1 more source

Species-Specificity of the BamA Component of the Bacterial Outer Membrane Protein-Assembly Machinery

, 2013
Elena B. Volokhina, Jan Grijpstra, Frank Beckers, Erika Lindh, Viviane Robert, Jan Tommassen, Martine P. Bos   +6 more
openalex   +2 more sources

A Multi‐Property Optimizing Generative Adversarial Network for de novo Antimicrobial Peptide Design

Advanced Science, EarlyView.
A Multi‐Property Optimizing Generative Adversarial Network (MPOGAN) is proposed to iteratively learn the relationship between peptides and multiple properties using a dynamically dataset. As the quality of the dataset improves, MPOGAN's ability to design antimicrobial peptides (AMPs) with multiple desired properties is enhanced.
Jiaming Liu, Tao Cui, Tao Wang, Lishan Lin, Xi Zeng, Dazhi Lu, Shaoqing Jiao, Jun Wang, Xiaoyan Li, Shuyuan Xiao, Dongna Xie, Xuecheng Wang, Yongtian Wang, Xuequn Shang, Yinbo Niu, Zhongyu Wei, Jiajie Peng   +16 more
wiley   +1 more source

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

Advanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu, Huitong Ruan, Xiaolin Zhang, Weihan Zheng, Muhetaierjiang Mutailifu, Ling Wang, Liu Yu, Ruijun Peng, Rui Zhao, Zihan Wang, Jie Xu, Shaochuan Li, Yaobin Wu, Wenguo Cui, Mujun Lu   +14 more
wiley   +1 more source

Dual recognition of multiple signals in bacterial outer membrane proteins enhances assembly and maintains membrane integrity. [PDF]

Elife
Germany EM, Thewasano N, Imai K, Maruno Y, Bamert RS, Stubenrauch CJ, Dunstan RA, Ding Y, Nakajima Y, Lai X, Webb CT, Hidaka K, Tan KS, Shen H, Lithgow T, Shiota T.   +15 more
europepmc   +1 more source

Control of Gene Expression at a Bacterial Leader RNA, the agn43 Gene Encoding Outer Membrane Protein Ag43 of Escherichia coli

, 2014
Anu Wallecha, Heather Oreh, Marjan W. van der Woude, Pieter L. deHaseth   +3 more
openalex   +1 more source

A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues

Advanced Science, EarlyView.
Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan, Xin Xu, Lin Huang, Dan Li, Yiran Deng, Xiangfei Xue, Susu Guo, Yiman Huang, Xiao Zhang, Yongchun Yu, Lifang Ma, Kun Qian, Jiayi Wang   +12 more
wiley   +1 more source

Enhancement of macrophage-mediated tumor cell killing by bacterial outer membrane proteins (porins) [PDF]

, 1983
Jason B. Weinberg, E. Ribi, Robert W. Wheat   +2 more
openalex   +1 more source

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

Advanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong, Wenyan Hao, Lingqi Xu, Yingyi Yang, Zhenzhen Dong, Peng Pan, Zhenjiang Bai, Jie Huang, Kaidi Yang, Zhu Jin, Rui Kang, Qiang Shan, Jiang huai Wang, Zijian Zhou, Daolin Tang, Jian Wang, Huiting Zhou   +16 more
wiley   +1 more source