Results 1 to 10 of about 6,396,996 (306)
A unifying mechanism for protein transport through the core bacterial Sec machinery [PDF]
Open Biology, 2023 Encapsulation and compartmentalization are fundamental to the evolution of cellular life, but they also pose a challenge: how to partition the molecules that perform biological functions—the proteins—across impermeable barriers into sub-cellular ...
William J. Allen, Ian Collinson
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Regulation of Protein Transport Pathways by the Cytosolic Hsp90s [PDF]
Biomolecules, 2022 The highly conserved molecular chaperone heat shock protein 90 (Hsp90) is well-known for maintaining metastable proteins and mediating various aspects of intracellular protein dynamics. Intriguingly, high-throughput interactome studies suggest that Hsp90
Anna G. Mankovich, Brian C. Freeman
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Proteomic screen reveals diverse protein transport between connected neurons in the visual system [PDF]
Cell Reports, 2022 Summary: Intercellular transfer of toxic proteins between neurons is thought to contribute to neurodegenerative disease, but whether direct interneuronal protein transfer occurs in the healthy brain is not clear.
Lucio M. Schiapparelli +10 more
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IFT-A Structure Reveals Carriages for Membrane Protein Transport into Cilia
Cell, 2022 Hesketh SJ +4 more
europepmc +2 more sources
Scientific Reports, 2021 Trichoderma reesei is an ascomycete fungus known for its capability to secrete high amounts of extracellular cellulose- and hemicellulose-degrading enzymes. These enzymes are utilized in the production of second-generation biofuels and T.
Sami Havukainen +5 more
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eLife, 2022 Nearly all mitochondrial proteins need to be targeted for import from the cytosol. For the majority, the first port of call is the translocase of the outer membrane (TOM complex), followed by a procession of alternative molecular machines, conducting ...
Holly C Ford +5 more
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Protein Transport through Nanopores Illuminated by Long-Time-Scale Simulations. [PDF]
ACS Nano, 2021 Mitscha-Baude G +3 more
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The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum
mBio, 2022 Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such as Mycobacterium tuberculosis and ...
Merel P. M. Damen +7 more
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Bacterial Signal Peptides- Navigating the Journey of Proteins
Frontiers in Physiology, 2022 In 1971, Blobel proposed the first statement of the Signal Hypothesis which suggested that proteins have amino-terminal sequences that dictate their export and localization in the cell.
Sharbani Kaushik +2 more
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Substrate-triggered position switching of TatA and TatB during Tat transport in Escherichia coli [PDF]
Open Biology, 2017 The twin-arginine protein transport (Tat) machinery mediates the translocation of folded proteins across the cytoplasmic membrane of prokaryotes and the thylakoid membrane of plant chloroplasts.
Johann Habersetzer +5 more
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