Results 31 to 40 of about 6,396,996 (306)

Transport outlook 2010: The potential for innovation [PDF]

open access: yes, 2010
This paper provides evidence on and discussion of recent developments in global transport markets and analyzes what policies look most promising for stabilizing CO2-emissions from light-duty vehicles.
International Transport Forum, OECD
core   +1 more source

Alternative trafficking of Weibel‐Palade body proteins in CRISPR/Cas9‐engineered von Willebrand factor–deficient blood outgrowth endothelial cells

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2019
Background Synthesis of the hemostatic protein von Willebrand factor (VWF) drives formation of endothelial storage organelles called Weibel‐Palade bodies (WPBs).
Maaike Schillemans   +11 more
doaj   +1 more source

Technical Note: The Use of RNA-interference as a Tool to Find Proteins Involved in Melanosome Formation or Transport [PDF]

open access: yes, 2009
Melanosomes are lysosome-related organelles that produce and transport the pigment melanin within melanocytes. Mutations in proteins required for melanosome transport and formation lead to a range of pigmentation defects, manifested at the cellular level
Daniela Rotin, Eva M. Amsen
core   +1 more source

An extracellular vesicle targeting ligand that binds to Arc proteins and facilitates Arc transport in vivo

open access: yeseLife, 2023
Communication between distant cells can be mediated by extracellular vesicles (EVs) that deliver proteins and RNAs to recipient cells. Little is known about how EVs are targeted to specific cell types.
Peter H Lee   +4 more
doaj   +1 more source

Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]

open access: yes, 2013
Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Estes, M. K.   +4 more
core   +3 more sources

Protein transport in organelles: Protein transport into and across the thylakoid membrane [PDF]

open access: yesThe FEBS Journal, 2009
The chloroplast thylakoid is the most abundant membrane system in nature, and is responsible for the critical processes of light capture, electron transport and photophosphorylation. Most of the resident proteins are imported from the cytosol and then transported into or across the thylakoid membrane. This minireview describes the multitude of pathways
Aldridge, C, Cain, P, Robinson, C
openaire   +2 more sources

Vesicular protein transport [PDF]

open access: yesThe Pharmacogenomics Journal, 2001
Protein transport and sorting in the secretory and endocytic pathways via vesicles is required for organelle biogenesis, constitutive and regulated secretion and constitutive and regulated endocytosis. It is essential for a multicellular organism and the function of its specialised cell types that the multiple transport and sorting events are highly ...
openaire   +2 more sources

Visualization of protein-protein interactions in the secretory pathway of mammalian cells [PDF]

open access: yes, 2006
An increasing number of human disorders are being linked to mutations in components of the secretory pathway. One example is combined blood coagulation factor V and VIII deficiency, an autosomal recessive disorder leading to hemophilia due to markedly ...
Nyfeler, Beat
core   +1 more source

Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2022
The biosynthetic transport route that constitutes the secretory pathway plays a fundamental role in the cell, providing to the synthesis and transport of around one third of human proteins and most lipids.
Simona Del Giudice   +5 more
doaj   +1 more source

Caudo‐rostral brain spreading of α‐synuclein through vagal connections

open access: yesEMBO Molecular Medicine, 2013
α‐Synuclein accumulation and pathology in Parkinson's disease typically display a caudo‐rostral pattern of progression, involving neuronal nuclei in the medulla oblongata at the earliest stages.
Ayse Ulusoy   +6 more
doaj   +1 more source

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