Results 11 to 20 of about 1,016,451 (162)
Transport o proteins into mitochondria [PDF]
Current Opinion in Cell Biology, 1989 The transfer of cytoplasmically synthesized precursor proteins into or across the inner mitochondrial membrane is dependent on energization of the membrane. To investigate the role of this energy requirement, a buffer system was developed in which efficient import of ADP/ATP carrier into mitochondria from the receptor-bound state occurred.
Pfanner, Nikolaus, Neupert, Walter
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Protein transport into mitochondria [PDF]
Current Opinion in Microbiology, 2000 Mitochondria are made up of two membrane systems that subdivide this organelle into two aqueous subcompartments: the matrix, which is enclosed by the inner membrane, and the intermembrane space, which is located between the inner and the outer membrane.
J M, Herrmann, W, Neupert
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The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum
mBio, 2022 Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such as Mycobacterium tuberculosis and ...
Merel P. M. Damen +7 more
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ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation
Journal of Lipid Research, 2015 ApoA-I, the main protein component of HDL, is suggested to be involved in metabolic homeostasis. We examined the effects of Milano, a naturally occurring ApoA-I variant, about which little mechanistic information is available.
Maria Lindahl +13 more
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Bacterial Signal Peptides- Navigating the Journey of Proteins
Frontiers in Physiology, 2022 In 1971, Blobel proposed the first statement of the Signal Hypothesis which suggested that proteins have amino-terminal sequences that dictate their export and localization in the cell.
Sharbani Kaushik +2 more
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Experimental Biology and Medicine, 1974 Rabbits were given intravenous injections of L-leucine 4,5/sup 3/H and L- leucine-/sup 12/C. The animals were killed at intervals up to 17h after the last injection and the lungs were removed and lavaged. After the lavage the lungs were minced and homogenized. Proteins were assayed for radioactivity.
K, Dickie, D, Massaro
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Conversion of the coprogen transport protein FhuE and the ferrioxamine B transport protein FoxA into ferrichrome transport proteins [PDF]
FEMS Microbiology Letters, 1998 The FhuA protein of Escherichia coli K-12 transports ferrichrome and the structurally related antibiotic albomycin across the outer membrane and serves as a receptor for the phages T1, T5, and phi 80 and for colicin M. In this paper, we show that chimeric proteins consisting of the central part of FhuA and the N- and C-terminal parts of FhuE (coprogen ...
H, Killmann, V, Braun
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Nucleoside Transporter Proteins
Current Vascular Pharmacology, 2009 Concentrative nucleoside transporters (CNT; SLC28) and equilibrative nucleoside transporters (ENT; SLC29) mediate the uptake of natural nucleosides and a variety of nucleoside-derived drugs, mostly used in anticancer therapy. SLC28 and SLC29 families consist in three and four members, respectively, which differ in their substrate selectivity and their ...
Molina-Arcas M +2 more
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Molecular Oncology, 2020 Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death.
Marta Pozniak +9 more
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Journal of Lipid Research, 2009 The mutant Chinese hamster ovary cell line MT58 contains a thermosensitive mutation in CTP:phosphocholine cytidylyltransferase, the regulatory enzyme in the CDP-choline pathway. As a result, MT58 cells have a 50% decrease in their phosphatidylcholine (PC)
Nicole Testerink +4 more
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