Results 21 to 30 of about 36,028 (200)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Understanding the development of bacterial colony: Physiology, new technology, and modeling
Quantitative BiologyBacterial colonies, as dynamic ecosystems, display intricate behaviors and organizational structures that profoundly influence their survival and functionality.
Jingwen Zhu, Pan Chu, Xiongfei Fu
doaj +1 more source
The microbe-free plant: fact or artefact?
Frontiers in Plant Science, 2011 Plant-microbe interactions are ubiquitous. Plants are often colonized by pathogens but even more commonly engaged in neutral or mutualistic interactions with microbes: below-ground microbial plant associates are mycorrhizal fungi, Rhizobia and ...
Laila P. Pamela Partida-Martinez +1 more
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Comparative genomics evidence that only protein toxins are tagging bad bugs
Frontiers in Cellular and Infection Microbiology, 2011 The term toxin was introduced by Roux and Yersin and describes macromolecular substances that, when produced during infection or when introduced parenterally or orally, cause an impairment of physiological functions that lead to disease or to the death ...
Kalliopi eGeorgiades, Didier eRaoult
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Resistencia antimicrobiana en pacientes de la comunidad
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019 Fundamento: los agentes causales de las infecciones en la comunidad y el comportamiento in vitro de la resistencia antimicrobiana difiere de los aislados en los hospitales.Objetivo: describir el patrón microbiológico de resistencia antimicrobiana de los ...
Zunilda Leticia Bello-Fernández +4 more
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Shaping of microbial phenotypes by trade-offs
Nature CommunicationsGrowth rate maximization is an important fitness strategy for microbes. However, the wide distribution of slow-growing oligotrophic microbes in ecosystems suggests that rapid growth is often not favored across ecological environments.
Manlu Zhu, Xiongfeng Dai
doaj +1 more source