Results 21 to 30 of about 36,248 (243)

The physiology and genetics of bacterial responses to antibiotic combinations

, 2022
Several promising strategies based on combining or cycling different antibiotics have been proposed to increase efficacy and counteract resistance evolution, but we still lack a deep understanding of the physiological responses and genetic mechanisms ...
Römhild, Roderich ; https://orcid.org/, Bollenbach, Mark Tobias ; https://orcid.org/, Andersson, Dan I.   +2 more
core   +2 more sources

In Silico Genome-Scale Reconstruction and Validation of the Staphylococcus aureus Metabolic Network [PDF]

, 2005
A genome-scale metabolic model of the Gram-positive, facultative anaerobic opportunistic pathogen Staphylococcus aureus N315 was constructed based on current genomic data, literature, and physiological information.
Panke, Sven, Heinemann, Matthias,, Kümmel, Anne, Ruinatscha, Reto,, Panke, Sven,, Heinemann, Matthias; id_orcid, Kümmel, Anne,, Ruinatscha, Reto, Heinemann, Matthias   +8 more
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Adhesion of oral streptococci to enamel and dental materials : studies using a flow chamber and microcalorimetry [PDF]

, 2007
Dental plaque formation on human teeth is the crucial etiologic factor in the pathogenesis of oral diseases: caries, periodontal diseases, and peri-implantitis.
Hauser-Gerspach, Irmgard
core   +1 more source

Self-organized enhancement of conductivity in biological ion channels [PDF]

, 2013
We discuss an example of self-organization in a biological system. It arises from long-range ion–ion interactions, and it leads us to propose a new kind of enhanced conduction in ion channels.
Kaufman, Igor, Khovanov, I. A., Khovanov, Igor A., McClintock, P. V. E., Eisenberg, Robert S., Luchinsky, Dmittri G., McClintock, Peter V. E., Eisenberg, R. S., Luchinsky, Dmitrii G., Tindjong, Rodrigue   +9 more
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Comparative analyses imply that the enigmatic Sigma factor 54 is a central controller of the bacterial exterior. [PDF]

, 2011
Contains fulltext : 95738.pdf (Publisher’s version ) (Open Access)BACKGROUND: Sigma-54 is a central regulator in many pathogenic bacteria and has been linked to a multitude of cellular processes like nitrogen assimilation and important ...
Roland J Siezen, Overmars, L., Moezelaar, R., Groot Kormelink Tom, Hagemeijer, Y., Sluijter Vincent, Siezen Roland J, Tom Groot Kormelink, Sluijter, V., Yanick Hagemeijer, Lex Overmars, Vincent Sluijter, Francke, C., Francke Christof, Hagemeijer Yanick, Overmars Lex, Christof Francke, Moezelaar Roy, Groot Kormelink, T., Roy Moezelaar, Siezen, R.J.   +20 more
core   +1 more source

Bacterial Networks on Hydrophobic Micropillars [PDF]

, 2017
Bacteria have evolved as intelligent microorganisms that can colonize and form highly structured and cooperative multicellular communities with sophisticated singular and collective behaviors.
Shahsavan, Hamed, Gu, Frank X, Mofrad, Mohammad RK, Hamed Shahsavan (1859020), Jahed, Zeinab, Jacob L. Rogowski (3625358), Ting Y. Tsui (805856), Frank X. Gu (805855), Rogowski, Jacob L, Zhao, Boxin, Zeinab Jahed (805854), Boxin Zhao (1418635), Tsui, Ting Y, Verma, Mohit S, Seo, Brandon B, Brandon B. Seo (805851), Mohammad R. K. Mofrad (218868), Mohit S. Verma (805853)   +17 more
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Profiling the effect of nafcillin on HA-MRSA D712 using bacteriological and physiological media [PDF]

, 2019
Staphylococcus aureus strains have been continuously evolving resistance to numerous classes of antibiotics including methicillin, vancomycin, daptomycin and linezolid, compounding the enormous healthcare and economic burden of the pathogen.
Meehan, Michael, Pogliano, Joe, Olson, Connor A., Palsson, Bernhard O, Sugie, Joseph, Szubin, Richard, Dorrestein, Pieter C., Lamsa, Anne, Knight, Rob, Olson, Connor A, Rajput, Akanksha, Feist, Adam M., Tsunemoto, Hannah, Seif, Yara, Dillon, Nicholas, Poudel, Saugat, Dorrestein, Pieter C, Monk, Jonathan M, Vrbanac, Alison, Feist, Adam M, Monk, Jonathan M., Dahesh, Samira, Nizet, Victor, Palsson, Bernhard O.   +23 more
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Comprehensive assessment of bacterial community viability in natural whey starter cultures by flow cytometric approach

, 2023
The natural whey starter consists of a lactic microbial community perpetuated daily by fermenting the whey from the previous day’s processing. These natural cultures play a crucial role in the acidification process of the cheese mass, which must lead ...
Morelli Lorenzo, Fontana Alessandra, Bellassi Paolo   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Physiological Basis for Nonheritable Antibiotic Resistance

, 2020
Antibiotics constitute one of the cornerstones of modern medicine. However, individuals may succumb to a bacterial infection if a pathogen survives exposure to antibiotics.
Mauricio H. Pontes, Eduardo A. Groisman
core   +1 more source