Results 41 to 50 of about 98,196 (235)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparative genomics evidence that only protein toxins are tagging bad bugs

Frontiers in Cellular and Infection Microbiology, 2011
The term toxin was introduced by Roux and Yersin and describes macromolecular substances that, when produced during infection or when introduced parenterally or orally, cause an impairment of physiological functions that lead to disease or to the death ...
Kalliopi eGeorgiades, Didier eRaoult
doaj   +1 more source

A Characterization of Scale Invariant Responses in Enzymatic Networks [PDF]

, 2012
An ubiquitous property of biological sensory systems is adaptation: a step increase in stimulus triggers an initial change in a biochemical or physiological response, followed by a more gradual relaxation toward a basal, pre-stimulus level.
A Asthagiri, A Grossman, A Kremling, A Ma'ayan, BA Mello, C Cohen-Saidon, C Widmann, CY Huang, D Angeli, D Lew, E Sontag, E Sontag, Eduardo D. Sontag, G Yao, GWO R Mesibov, H Chen, J Bijlsma, J Tsang, K Takeda, L Bleris, L Chang, L Goentoro, LA Ridnour, M Sulis, Maja Skataric, Mark S. Alber, MD Lazova, MP Mahaut-Smith, NA Shah, O Shoval, O Shoval, P Francois, P Iglesias, P Menè, R Nesher, RL Iman, S Donovan, S Mangan, S Marsigliante, S Paliwal, S Sasagawa, SM Block, T Nagashima, TM Yi, TS Shimizu, W Ma, YV Kalinin   +46 more
core   +5 more sources

Analytic philosophy for biomedical research: the imperative of applying yesterday's timeless messages to today's impasses [PDF]

, 2020
The mantra that "the best way to predict the future is to invent it" (attributed to the computer scientist Alan Kay) exemplifies some of the expectations from the technical and innovative sides of biomedical research at present.
A Armiento, A Gare, A Hilfinger, A Karmon, A Lin, A Ross-Gillespie, A Sekikawa, A Zuniga, AA Thompson, AC Oates, AD Asatryan, AI Tauber, AL Byrd, AM Hosios, AM Jaeger, AP Monaco, B Berger, B Rehermann, BP Abbott, BW O’Malley, C Glymour, C Kadelka, C Willyard, CA Tulk, CN Bagot, Collaboration Open Science, CT Walsh, D Reker, D Wallach, DC Clary, DJ Depew, DJ Nicholson, DP Norris, DY Gouvêa, E Bizzi, E Del Soldato, E Piskounova, E Toprak, Editors, EJ Louis, F Davidoff, F Leigh, F Rohwer, FE Abbot, GJ Romanes, GJ Toomer, GM Bodner, GM Brodeur, H Braak, H Ledford, H Varmus, HB Frieboes, HJ Anders, HL Van Epps, HM Lopez, HS Chung, I Brigandt, IL Markov, IM Lonie, J Couzin-Frankel, J Dong, J Elf, J Greene, J Gunawardena, J Gunawardena, J Lister, J Manchak, J Odenbaugh, J Raspopovic, J Su, JA Barnett, JC Cardwell, JE Allen, JF Fisher, JH Woodger, JI Seeman, JJ McNeil, JM Barry, JM Tanner, JN Weiss, JP Capp, JP Robinson, JRA, JS Steffan, JT Leek, K Arney, K Lewis, K Neupane, K Servick, K Shrinivas, KT Smith, L Tadrist, LA DiMeglio, LA Hug, M Baym, M Buchanan, M Delling, M Friedman, M Greaves, M Kramer, M Levin, M Nei, M Niepel, M Pigliucci, M Schaapveld, M Thamer, MA McCormick, MB Everaert, MC Marchetti, MD Hauser, ME Feder, N Chomsky, N Chomsky, N Yang, N Yucel, NQ Balaban, OR Jones, P Bauer, P Griffiths, P Lieshout, P McNamara, P Robustelli, Plato, PN Singer, Q Justman, Q Zhong, R Chatterjee, R Chen, R Gregory, R Kolter, R Losick, R MacCoun, R Scholl, RC Berwick, RC Lewontin, RJ Britten, RL Wasserstein, RM Nesse, RV Christie, RZ Moger-Reischer, S Bartley, S Cukierman, S Gordon, S Kannan, S Kryazhimskiy, S Ling, S Smit, S Uphoff, S Wong, SA Hoption Cann, SH Orzack, SJ Biller, SJ Diede, SM Connell, SM Fleming, SM Mozaffari, TA Carey, TE Kottke, TG Nakashige, V Lazar, W Shou, W Szybalski, WD Casebeer, X Wei, XS Xie, Y Hatwalne, YE Nikiforov   +166 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source

Resistencia antimicrobiana en pacientes de la comunidad

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Fundamento: los agentes causales de las infecciones en la comunidad y el comportamiento in vitro de la resistencia antimicrobiana difiere de los aislados en los hospitales.Objetivo: describir el patrón microbiológico de resistencia antimicrobiana de los ...
Zunilda Leticia Bello-Fernández, Yacel Pacheco-Pérez, Pedro Enrique Castillo-Pompa, Juan Núñez-Chacón, Yaquelin Cozme-Rojas   +4 more
doaj  

Shaping of microbial phenotypes by trade-offs

Nature Communications
Growth rate maximization is an important fitness strategy for microbes. However, the wide distribution of slow-growing oligotrophic microbes in ecosystems suggests that rapid growth is often not favored across ecological environments.
Manlu Zhu, Xiongfeng Dai
doaj   +1 more source

Identification and Population Estimation of Epiphytic Ice Nucleation Active Bacteria Isolated from Stone Fruit Trees in Khorasan-Razavi Province

Majallah-i ḥifāẓat-i giyāhān, 2016
Introduction: Epiphytic bacteria are common inhabitants of plant leaflet surfaces and can have important influences on the plants on which they live. Accurate estimates of epiphytic bacterial population sizes are needed to detect their roles in several ...
E. Taheri, S. Tarighi, P. Taheri
doaj   +1 more source