Results 81 to 90 of about 1,915,591 (341)

Bacterial Superinfection Pneumonia in Patients Mechanically Ventilated for COVID-19 Pneumonia

American Journal of Respiratory and Critical Care Medicine, 2021
Rationale: Current guidelines recommend patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia receive empirical antibiotics for suspected bacterial superinfection on the basis of weak evidence.
C. Pickens, C. Gao, M. Cuttica, Sean B. Smith, L. Pesce, R. Grant, M. Kang, L. Morales-Nebreda, Avni A Bavishi, J. Arnold, A. Pawlowski, Chao Qi, G. S. Budinger, Benjamin D. Singer, R. Wunderink   +14 more
semanticscholar   +1 more source

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Demographic characteristics and opportunistic diseases associated with attrition during preparation for antiretroviral therapy in primary health centres in Kibera, Kenya. [PDF]

, 2011
Using routine data from HIV-positive adult patients eligible for antiretroviral therapy (ART), we report on routinely collected demographic characteristics and opportunistic diseases associated with pre-ART attrition (deaths and loss to follow-up). Among
Amuron, Anglaret, Boehme, Braitstein, Etard, Fox, Gilks, Gilks, Grant, Ingle, Ingle, Janoof, Jones, Larson, Lawn, Lawn, Lucas, Peters, Scott, Van Griensven, Zachariah   +20 more
core   +2 more sources

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

What Does it Mean When a Child is Diagnosed with Pneumonia?

Pediatric Respirology and Critical Care Medicine, 2019
Pneumonia is a frequent diagnosis without adequate consideration of the etiology. Pneumonia implies the presence of inflammation of the lung parenchyma with consolidation. That inflammation may be from infectious or noninfectious causes.
Miles Weinberger
doaj   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Clinical and Etiological Features of Community-acquired Pneumonia in Children in Vladivostok

Детские инфекции (Москва), 2015
A survey of 991 with community-acquired pneumonia. The disease is most proceeded in the average severity (97.2 %). In 99.4 % of cases diagnosed focal, polysegmental pneumonia in 0.6% of cases.
L. G. Erokhina, O. G. Savina, T. O. Svirinkova, M. A. Terpugova   +3 more
doaj   +1 more source

Point-of-care measurement of blood lactate in children admitted with febrile illness to an African District Hospital. [PDF]

, 2011
BACKGROUND: Lactic acidosis is a consistent predictor of mortality owing to severe infectious disease, but its detection in low-income settings is limited to the clinical sign of "deep breathing" because of the lack of accessible technology for its ...
Acierno, B. Amos, B. Nadjm, Day, English, English, English, F. Muro, G. Mtove, Gore, H. Reyburn, I. C. E. Hendriksen, J. Todd, Kahigwa, Krishna, Krishna, Maitland, Marsh, Marsh, Molyneux, Nadjm, Reyburn, Taylor   +22 more
core   +1 more source

Evidence-Based Study Design for Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia

Journal of Infectious Diseases, 2019
BACKGROUND The US Food and Drug Administration solicited evidence-based recommendations to improve guidance for studies of hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP).
G. Talbot, Anita F. Das, Stephanie S. Cush, A. Dane, M. Wible, R. Echols, A. Torres, S. Cammarata, J. Rex, J. Powers, T. Fleming, J. Loutit, S. Hoffmann   +12 more
semanticscholar   +1 more source