Results 141 to 150 of about 3,299,929 (298)

A SVM based approach to identification of Gram-negative bacterial secretion system proteins

四川大学学报. 自然科学版, 2016
A SVM based approach is proposed to rapidly identify Gram-negative bacterial secretion system proteins. With the optimization feature set consisted of amino acid composition (AAC) and position specific scoring matrix (PSSM), this method adequately takes ...
YU Le-Zheng, ZHAO Liu-Qing, CHEN Man, LUO Jie-Si, LIU Feng-Juan   +4 more
doaj  

Looking into key bacterial proteins involved in gut dysbiosis. [PDF]

World J Methodol, 2021
Zeng XY, Li M.
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Optimization of proteomics sample preparation for identification of host and bacterial proteins in mouse feces. [PDF]

Anal Bioanal Chem, 2022
Baniasad M, Kim Y, Shaffer M, Sabag-Daigle A, Leleiwi I, Daly RA, Ahmer BMM, Wrighton KC, Wysocki VH.   +8 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Assay for Assessing Mucin Binding to Bacteria and Bacterial Proteins. [PDF]

Bio Protoc, 2021
Grigoryeva LS, Rehman S, White RC, Garnett JA, Cianciotto NP.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation. [PDF]

Elife, 2021
Hajdusits B, Suskiewicz MJ, Hundt N, Meinhart A, Kurzbauer R, Leodolter J, Kukura P, Clausen T.   +7 more
europepmc   +1 more source

Bacterial iron-sulfur proteins [PDF]

Microbiological Reviews, 1979
D C, Yoch, R P, Carithers
openaire   +2 more sources