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Evolutionary pathways of repeat protein topology in bacterial outer membrane proteins [PDF]

open access: yeseLife, 2018
Outer membrane proteins (OMPs) are the proteins in the surface of Gram-negative bacteria. These proteins have diverse functions but a single topology: the β-barrel.
Meghan Whitney Franklin   +5 more
doaj   +4 more sources

Dual recognition of multiple signals in bacterial outer membrane proteins enhances assembly and maintains membrane integrity [PDF]

open access: yeseLife
Outer membrane proteins (OMPs) are essential components of the outer membrane of Gram-negative bacteria. In terms of protein targeting and assembly, the current dogma holds that a ‘β-signal’ imprinted in the final β-strand of the OMP engages the β-barrel
Edward M Germany   +15 more
doaj   +2 more sources

Extraction and Electrophoretic Analysis of Bacterial Lipopolysaccharides and Outer Membrane Proteins

open access: yesBio-Protocol, 2021
Lipopolysaccharides (LPS) (or lipooligosaccharides [LOS], which lack the O-antigen side chains characteristic of LPS), and outer membrane proteins (OMP) are major cell-surface molecules in the outer membrane (OM) of gram-negative bacteria.
Yue Lee, Thomas Inzana
doaj   +3 more sources

Bacterial outer membrane proteins assemble via asymmetric interactions with the BamA β-barrel [PDF]

open access: yesNature Communications, 2019
The integration of β-barrel proteins into the bacterial outer membrane (OM) is catalysed by the β-barrel assembly machinery (BAM). Here authors develop a method to trap an E.
Matthew T. Doyle, Harris D. Bernstein
doaj   +2 more sources

Exploring bacterial outer membrane barrier to combat bad bugs [PDF]

open access: yesInfection and Drug Resistance, 2017
Ishan Ghai,1 Shashank Ghai2 1School of Engineering and Life Sciences, Jacobs University, Bremen, 2Leibniz University, Hannover, Germany Abstract: One of the main fundamental mechanisms of antibiotic resistance in Gram-negative bacteria comprises an ...
Ghai I, Ghai S
doaj   +2 more sources

Vesicle Nucleation Peptide Fusion Induced Extracellular Vesicles Are Distinct From Escherichia coli Outer Membrane Vesicles, and Provide an Enhanced Platform for Protein Production and Purification [PDF]

open access: yesJournal of Extracellular Vesicles
Bacterial outer membrane vesicles (OMVs) are nano‐sized, spherical structures released by Gram‐negative bacteria that play diverse roles in bacterial physiology, including communication, nutrient acquisition and host interactions. These vesicles bud from
Bree R. Streather   +9 more
doaj   +2 more sources

Entry and exit of bacterial outer membrane proteins. [PDF]

open access: yesTrends Microbiol, 2015
The sites of new outer membrane protein (OMP) deposition and the fate of pre-existing OMPs are still enigmatic despite numerous concerted efforts. Rassam et al. identified mid-cell regions as the primary entry points for new OMP insertion in clusters, driving the pre-existing OMP clusters towards cell poles for long-term storage.
Misra R.
europepmc   +3 more sources

The Ton Motor

open access: yesFrontiers in Microbiology, 2022
The Ton complex is a molecular motor at the inner membrane of Gram-negative bacteria that uses a proton gradient to apply forces on outer membrane (OM) proteins to permit active transport of nutrients into the periplasmic space.
Anna C. Ratliff   +2 more
doaj   +1 more source

Outer Membrane Vesicles Released From Aeromonas Strains Are Involved in the Biofilm Formation

open access: yesFrontiers in Microbiology, 2021
Aeromonas spp. are Gram-negative rod-shaped bacteria ubiquitously distributed in diverse water sources. Several Aeromonas spp. are known as human and fish pathogens.
Soshi Seike   +5 more
doaj   +1 more source

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