Results 41 to 50 of about 3,626,493 (277)
Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis [PDF]
, 2009 The bacterial PorB porin, an ATP-binding beta-barrel protein of pathogenic Neisseria gonorrhoeae, triggers host cell apoptosis by an unknown mechanism. PorB is targeted to and imported by host cell mitochondria, causing the breakdown of the mitochondrial
Kepp, Oliver +45 more
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Bacterial Outer Membranes and Interactions with Membrane Proteins [PDF]
Biophysical Journal, 2015 Because the bacteria's outer membrane (OM) acts as an effective barrier against the permeation of both hydrophobic and hydrophilic compounds, gram-negative cell permeation is one of the biggest challenges to the discovery of novel antibiotics for bacterial infections and antibiotic resistance worldwide.
openaire +1 more source
Structural characterisation of outer membrane proteins from Borrelia burgdorferi sensu lato by small-angle X-ray scattering [PDF]
, 2016 Forming the interface between the bacterial cell and the host, the outer membrane of Borrelia is known to play a key role in pathogenicity. Although Borrelia burgdorferi sensu lato are considered to be Gram-negative, their outer membrane is unique ...
Stejskal, Lenka
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Prediction of β-barrel membrane proteins by searching for restricted domains [PDF]
, 2005 BACKGROUND: The identification of beta-barrel membrane proteins out of a genomic/proteomic background is one of the rapidly developing fields in bioinformatics. Our main goal is the prediction of such proteins in genome/proteome wide analyses.
Mirus, O. +5 more
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BMC Genomics, 2009 Background Chlamydiae are obligate intracellular bacteria comprising some of the most important bacterial pathogens of animals and humans. Although chlamydial outer membrane proteins play a key role for attachment to and entry into host cells, only few ...
Myers Garry +5 more
doaj +1 more source
Structure and function of bacterial dynamin-like proteins [PDF]
, 2012 Membrane dynamics are essential for numerous cellular processes in eukaryotic and prokaryotic cells. In eukaryotic cells, membrane fusion and fission are often catalyzed by large GTPases of the dynamin protein family. These proteins couple GTP hydrolysis
Bramkamp, Marc
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The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]
, 2015 The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Brown, G. +9 more
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Dissecting Escherichia coli outer membrane biogenesis using differential proteomics. [PDF]
PLoS ONE, 2014 The cell envelope of Gram-negative bacteria is a complex multi-layered structure comprising an inner cytoplasmic membrane and an additional asymmetric lipid bilayer, the outer membrane, which functions as a selective permeability barrier and is essential
Alessandra M Martorana +7 more
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Stress-Responsive Periplasmic Chaperones in Bacteria
Frontiers in Molecular Biosciences, 2021 Periplasmic proteins are involved in a wide range of bacterial functions, including motility, biofilm formation, sensing environmental cues, and small-molecule transport. In addition, a wide range of outer membrane proteins and proteins that are secreted
Hyunhee Kim +4 more
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Bio-Protocol, 2020 Bacterial outer membrane vesicles (OMVs) are naturally formed by budding from the outer membrane of Gram-negative bacteria. OMVs consist of a lipid bilayer identical in composition to the original outer membrane and contain periplasmic content within ...
Johannes Thoma, Björn Burmann
doaj +1 more source