Results 61 to 70 of about 273,841 (296)

Interactions between folding factors and bacterial outer membrane proteins [PDF]

Molecular Microbiology, 2005
SummaryThe outer membrane is the first line of contact between Gram‐negative bacteria and their external environment. Embedded in the outer membrane are integral outer membrane proteins (OMPs) that perform a diverse range of tasks. OMPs are synthesized in the cytoplasm and are translocated across the inner membrane and probably diffuse through the ...
Mogensen, Jesper E., Otzen, Daniel E.
openaire   +3 more sources

Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins

mBio, 2017
The Gram-negative bacterial cell wall component lipopolysaccharide (LPS) is recognized by the noncanonical inflammasome protein caspase-11 in the cytosol of infected host cells and thereby prompts an inflammatory immune response linked to sepsis.
Ryan Finethy, Sarah Luoma, Nichole Orench-Rivera, Eric M. Feeley, Arun K. Haldar, Masahiro Yamamoto, Thirumala-Devi Kanneganti, Meta J. Kuehn, Jörn Coers   +8 more
doaj   +1 more source

The Landscape of Pseudomonas aeruginosa Membrane-Associated Proteins

Cells, 2020
Background: Pseudomonas aeruginosa cell envelope-associated proteins play a relevant role in infection mechanisms. They can contribute to the antibiotic resistance of the bacterial cells and be involved in the interaction with host cells.
Sara Motta, Davide Vecchietti, Alessandra M. Martorana, Pietro Brunetti, Giovanni Bertoni, Alessandra Polissi, Pierluigi Mauri, Dario Di Silvestre   +7 more
doaj   +1 more source

Oxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space [PDF]

, 2016
Mitochondria are organelles that play a central role in cellular metabolism, as they are responsible for processes such as iron/sulfur cluster biogenesis, respiration and apoptosis.
MacPherson, Lisa, Manganas, Phanee, Tokatlidis, Kostas   +2 more
core   +1 more source

Structure and function of bacterial outer membrane proteins: barrels in a nutshell [PDF]

Molecular Microbiology, 2000
The outer membrane protects Gram‐negative bacteria against a harsh environment. At the same time, the embedded proteins fulfil a number of tasks that are crucial to the bacterial cell, such as solute and protein translocation, as well as signal transduction.
Koebnik, Ralf, Locher, Kaspar, van Gelder, Patrick   +2 more
openaire   +3 more sources

Mucin adsorbed by E. coli can affect neutrophil activation in vitro

FEBS Open Bio, 2020
Bacteria colonizing human intestine adhere to the gut mucosa and avoid the innate immune system. We previously demonstrated that Escherichia coli isolates can adsorb mucin from a diluted solution in vitro.
Elena Mikhalchik, Nadezhda Balabushevich, Tatiana Vakhrusheva, Alexey Sokolov, Julia Baykova, Daria Rakitina, Petr Scherbakov, Sergey Gusev, Alexander Gusev, Zaira Kharaeva, Olga Bukato, Olga Pobeguts   +11 more
doaj   +1 more source

Spirochetal Lipoproteins and Immune Evasion. [PDF]

, 2017
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani, Christodoulides, Alexei, Kelesidis, Theodoros   +2 more
core   +1 more source

Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes [PDF]

Nature Communications, 2014
In biological membranes, various protein secretion devices function as nanomachines, and measuring the internal movements of their component parts is a major technological challenge. The translocation and assembly module (TAM) is a nanomachine required for virulence of bacterial pathogens. We have reconstituted a membrane containing the TAM onto a gold
Shen, Hsin-Hui, Leyton, Denisse, Shiota, Takuya, Belousoff, Matthew J, Noinaj, Nicholas, Lu, Jingxiong, Holt, Stephen A., Tan, Kershing, Selkrig, Joel, Webb, Chaille T., Buchanan, Susan K., Martin, Lisandra, Lithgow, Trevor   +12 more
openaire   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The participation of outer membrane proteins in the bacterial sensitivity to nanosilver

Postępy Higieny i Medycyny Doświadczalnej, 2016
The presented study is to analyze the participation of outer membrane proteins of Gram- negative bacteria in sensitivity to silver nanomaterials. The mechanism of interaction of silver with the bacterial cell is best described in this group of microorganisms.
Anna, Kędziora, Eva, Krzyżewska, Bartłomiej, Dudek, Gabriela, Bugla-Płoskońska   +3 more
openaire   +2 more sources