Results 81 to 90 of about 273,841 (296)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

XatA, an AT-1 autotransporter important for the virulence of Xylella fastidiosa Temecula1. [PDF]

, 2012
Xylella fastidiosa Temecula1 is the causative agent of Pierce's disease of grapevine, which is spread by xylem-feeding insects. An important feature of the infection cycle is the ability of X.
Huston, Sherry L, Igo, Michele M, Killiny, Nabil, Matsumoto, Ayumi   +3 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Socializing, networking and development: a report from the second ‘Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis’ [PDF]

, 2012
In mid-June, the second Young Microbiologists Symposium took place under the broad title of ‘Microbe signalling, organization and pathogenesis’ on the picturesque campus of University College Cork, Ireland.
Barret, Brackman, Brown, Bush, Cascales, Corrigan, Costerton, Coulthurst, D'Autreaux, Davey, Delalez, Fazli, Gerlach, Hagan, Holland, Hood, Housden, Kleanthous, Kuchma, Kuchma, Kuchma, Lawley, Lebeer, Malone, McCarthy, Merritt, Murdoch, O'Connell Motherway, O'Connell Motherway, O'Toole, Porter, Ramsay, Ramsay, Rigel, Roberts, Ryan, Ryan, Ryan, Ryan, Ryan, Schwarz, Sharma, Shioya, Smith, Thompson, Twomey, Waters, Yang, Youle   +48 more
core   +1 more source

Acquisition of ionic copper by a bacterial outer membrane protein [PDF]

, 2020
Abstract Copper, while toxic in excess, is an essential micronutrient in all kingdoms of life due to its essential role in the structure and function of many proteins. Proteins mediating ionic copper import have been characterised in detail for eukaryotes, but much less so for prokaryotes.
Satya Prathyusha Bhamidimarri, Tessa R. Young, Muralidharan Shanmugam, Sandra Soderholm, Arnaud Baslé, Dirk Bumann, Bert van den Berg   +6 more
openaire   +1 more source

MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis

Scientific Reports, 2017
Bacterial proteins with MCE domains were first described as being important for Mammalian Cell Entry. More recent evidence suggests they are components of lipid ABC transporters.
Georgia L. Isom, Nathaniel J. Davies, Zhi-Soon Chong, Jack A. Bryant, Mohammed Jamshad, Maria Sharif, Adam F. Cunningham, Timothy J. Knowles, Shu-Sin Chng, Jeffrey A. Cole, Ian R. Henderson   +10 more
doaj   +1 more source

LytM Proteins Play a Crucial Role in Cell Separation, Outer Membrane Composition, and Pathogenesis in Nontypeable Haemophilus influenzae

mBio, 2015
LytM proteins belong to a family of bacterial metalloproteases. In Gram-negative bacteria, LytM factors are mainly reported to have a direct effect on cell division by influencing cleavage and remodeling of peptidoglycan.
Giuseppe Ercoli, Chiara Tani, Alfredo Pezzicoli, Irene Vacca, Manuele Martinelli, Simone Pecetta, Roberto Petracca, Rino Rappuoli, Mariagrazia Pizza, Nathalie Norais, Marco Soriani, Beatrice Aricò   +11 more
doaj   +1 more source

Plasticity within the barrel domain of BamA mediates a hybrid-barrel mechanism by BAM

Nature Communications, 2021
The β-barrel assembly machinery (BAM) assists the folding and membrane insertion of bacterial outer membrane proteins. Here, the authors report structural characterization of BAM in lipid environment and in complex with the client protein EspP integrated
Runrun Wu, Jeremy W. Bakelar, Karl Lundquist, Zijian Zhang, Katie M. Kuo, David Ryoo, Yui Tik Pang, Chen Sun, Tommi White, Thomas Klose, Wen Jiang, James C. Gumbart, Nicholas Noinaj   +12 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

The VgrG Proteins Are "à la Carte" Delivery Systems for Bacterial Type VI Effectors [PDF]

, 2014
The bacterial type VI secretion system (T6SS) is a supra-molecular complex akin to bacteriophage tails, with VgrG proteins acting as a puncturing device. The Pseudomonas aeruginosa H1-T6SS has been extensively characterized.
Allsopp, LP, Filloux, A, Hachani, A, Oduko, Y   +3 more
core   +2 more sources