Results 71 to 80 of about 3,626,493 (277)

The participation of outer membrane proteins in the bacterial sensitivity to nanosilver

Postępy Higieny i Medycyny Doświadczalnej, 2016
The presented study is to analyze the participation of outer membrane proteins of Gram- negative bacteria in sensitivity to silver nanomaterials. The mechanism of interaction of silver with the bacterial cell is best described in this group of microorganisms.
Anna, Kędziora, Eva, Krzyżewska, Bartłomiej, Dudek, Gabriela, Bugla-Płoskońska   +3 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Structural and functional studies of bacterial outer membrane lipopolysaccharide insertion and Schmallenberg virus replication [PDF]

, 2015
Lipopolysaccharide (LPS) is an essential component of the outer membrane (OM) of Gram-negative bacteria and plays a fundamental role in protecting the bacteria from harsh environments and toxic compounds.
Dong, Haohao
core   +2 more sources

The invariant phenylalanine of precursor proteins discloses the importance of Omp85 for protein translocation into cyanelles [PDF]

, 2007
Background Today it is widely accepted that plastids are of cyanobacterial origin. During their evolutionary integration into the metabolic and regulatory networks of the host cell the engulfed cyanobacteria lost their independency.
Schleiff Enrico, Roman Martin, Martin, Roman, Schleiff, Enrico (Ludwig-Maximilians-Universität München (LMU)), Steiner Jürgen M, Steiner, Jürgen M., Loeffelhardt, Wolfgang, Wunder, Tobias (Ludwig-Maximilians-Universität München (LMU)), Löffelhardt Wolfgang, Steiner, Juergen M., Wunder Tobias, Martin, Roman (Ludwig-Maximilians-Universität München (LMU)), Tobias Wunder, Enrico Schleiff, Jürgen M Steiner, Martin Roman, Wunder, Tobias, Löffelhardt, Wolfgang (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Schleiff, Enrico, Löffelhardt, Wolfgang, Steiner, Juergen-Michael (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Wolfgang Löffelhardt   +21 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Characterization of Translocation Contact Sites Involved in the Import of Mitochondrial Proteins [PDF]

, 1987
Import of proteins into the mitochondrial matrix requires translocation across two membranes. Translocational intermediates of mitochondrial proteins, which span the outer and inner membrane simultaneously and thus suggest that translocation occurs in ...
Herzog, Volker, W Neupert, Schwaiger, Martin, M Schwaiger, Neupert, Walter, V Herzog   +5 more
core   +2 more sources

Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion [PDF]

, 2015
BAM is a conserved molecular machine, the central component of which is BamA. Orthologues of BamA are found in all Gram-negative bacteria, chloroplasts and mitochondria where it is required for the folding and insertion of β-barrel containing integral ...
Jeeves, Mark, Mason, Jessica L, Knowles, Timothy J., Rossiter, Amanda E, Rossiter, Amanda E.; id_orcid, Browning, Douglas F., Bavro, Vassiliy N., Henderson, Ian R., Cunningham, Adam F., Overduin, Michael, Sevastsyanovich, Yanina R., Rossiter, Amanda E., Donald, James W., Browning, Douglas F, Wells, Timothy J, Henderson, Ian R, Knowles, Timothy J.; id_orcid, Wells, Timothy J., Palmer, Tracy, Knowles, Timothy J, Sevastsyanovich, Yanina R, Cunningham, Adam F, Mason, Jessica L., Bavro, Vassiliy N, Donald, James W   +24 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Analyzing the molecular mechanism of lipoprotein localization in Brucella

Frontiers in Microbiology, 2015
Bacterial lipoproteins possess comprehensive structure and functionality, ranging from bacterial physiology to pathogenic processes. As such many lipoproteins, originating from Brucella are exploited as potential vaccines to countermeasure brucellosis ...
Shivani eGoolab, Shivani eGoolab, Robyn Lindsay Roth, Henriette evan Heerden, Michael Craig Crampton   +4 more
doaj   +1 more source

Membrane Protein Simulations: Ion Channels And Bacterial Outer Membrane Proteins

, 2003
Publisher Summary The chapter focuses on two classes that have been investigated by a number of research groups—namely, ion channels and bacterial outer membrane proteins—rather than attempt to cover all simulations of membrane proteins. Ion channels play a key role in the electrical activity of cells of the nervous system. However, channels are also
Domene, Carmen, Bond, Peter J, Sansom, Mark S   +2 more
openaire   +3 more sources