Results 91 to 100 of about 273,841 (296)

The simulation approach to bacterial outer membrane proteins.

Molecular Membrane Biology, 2016
The outer membrane of Gram-negative bacteria serves as a protective barrier against the external environment but is rendered selectively permeable to nutrients and waste by proteins called porins. Other outer membrane proteins (OMPs) provide the membrane with a variety of other functions including active transport, catalysis, pathogenesis and signal ...
Bond, P, Sansom, MS
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Membranes by the Numbers [PDF]

, 2017
Many of the most important processes in cells take place on and across membranes. With the rise of an impressive array of powerful quantitative methods for characterizing these membranes, it is an opportune time to reflect on the structure and function ...
A Finkelstein, A Flamholz, A Nenninger, A Pockels, A Schmidt, A Upadhyaya, AD Dupuy, AE Shyer, AF Bitbol, C Klose, C Klose, C Nielsen, C Tanford, CS Ejsing, D Boal, D Chow, E Evans, E Gorter, E Layre, E Richardson, ES Haswell, FC Neidhardt, FM Hochmuth, G Meer van, GS Manning, GW Li, H Fricke, HC Gaede, HG Garcia, HJ Curtis, I Langmuir, I Vorobyov, J Dai, J Peukes, J Schlessinger, J Song, JB Dacks, JF Nagle, JF Nagle, JF Nagle, JL Sampaio, JT Mika, KC Olbrich, KR Levental, L Bintu, L Fagerberg, L Kalvodova, LK Buehler, M Bialecka-Fornal, M Carvalho, M Kumar, M Li, M Louhivuori, Maya Shamir, MC Field, MK Doeven, MR Alecio, O Kedem, OS Andersen, P Sens, PF Fahey, PG Saffman, R Milo, R Milo, R Phillips, R Phillips, R Phillips, RW Robinett, S Mahajan, S Ramadurai, S Takamori, T Hanai, T Savin, TA Harroun, U Seifert, Uri Moran, W Almers, W Bialek, W Rawicz, Walter Neupert, WD Stein, Y Gambin, Y Shibata, Y Shibata   +83 more
core   +2 more sources

Novel sterol binding domains in bacteria

eLife
Sterol lipids are widely present in eukaryotes and play essential roles in signaling and modulating membrane fluidity. Although rare, some bacteria also produce sterols, but their function in bacteria is not known.
Liting Zhai, Amber C Bonds, Clyde A Smith, Hannah Oo, Jonathan Chiu-Chun Chou, Paula V Welander, Laura MK Dassama   +6 more
doaj   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

The ‘porin-cytochrome’ model for microbe-to-mineral electron transfer [PDF]

, 2012
Many species of bacteria can couple anaerobic growth to the respiratory reduction of insoluble minerals containing Fe(III) or Mn(III/IV). It has been suggested that in Shewanella species electrons cross the outer membrane to extracellular substrates via ‘
Afkar, Baron, Bouhenni, Burns, Cao, Clarke, Clarke, Clarke, Coursolle, DiChristina, Dohnalkova, Donald, Eggleston, El-Naggar, Firer-Sherwood, Firer-Sherwood, Gorby, Gralnick, Hartshorne, Hartshorne, Heidelberg, Jensen, Jiang, Jiao, Johs, Kerisit, Leang, Lies, Liu, Lower, Lower, Lower, Malvankar, Malvankar, Marsili, McLean, Meitl, Myers, Peretyazhko, Pessanha, Qian, Reardon, Reguera, Reguera, Roessler, Ross, Schuetz, Shi, Shi, Smith, Strycharz-Glaven, Strycharz-Glaven, Taylor, von Canstein, Xiong, Zargar, Zhang, Zhang   +57 more
core   +2 more sources

Protective Immune Responses Induced in Chickens by Outer Membrane Proteins Extracted from Different Strains of Escherichia coli

Iranian Journal of Allergy, Asthma and Immunology, 2004
Different strains of Escherichia coli (E. coli) from human, chickens, and the common strain between human and chickens were isolated and typed with mono-specific antibody. The E. coli strains from each group of human, chicken and common between human and
Farhad Vaez zadeh, Farhad Esmaily, Mohammad Kazem Sharifi-Yazdi   +2 more
doaj  

Scaffolding Protein GspB/OutB Facilitates Assembly of the Dickeya dadantii Type 2 Secretion System by Anchoring the Outer Membrane Secretin Pore to the Inner Membrane and to the Peptidoglycan Cell Wall

mBio, 2022
The phytopathogenic proteobacterium Dickeya dadantii secretes an array of plant cell wall-degrading enzymes and other virulence factors via the type 2 secretion system (T2SS).
Shiheng Zhang, Shuang Gu, Piers Rycroft, Florence Ruaudel, Frederic Delolme, Xavier Robert, Lionel Ballut, Richard W. Pickersgill, Vladimir E. Shevchik   +8 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Bacterial Origin of a Mitochondrial Outer Membrane Protein Translocase [PDF]

Journal of Biological Chemistry, 2012
Mitochondria are of bacterial ancestry and have to import most of their proteins from the cytosol. This process is mediated by Tom40 an essential protein that forms the protein translocating pore in the outer mitochondrial membrane. Tom40 is conserved in virtually all eukaryotes but its evolutionary origin is unclear because bacterial orthologues have ...
Harsman Anke, Niemann Moritz, Pusnik Mascha, Schmidt Oliver, Burmann Björn M, Hiller Sebastian, Meisinger Chris, Schneider André, Wagner Richard   +8 more
openaire   +1 more source