Not All Bacterial Outer-Membrane Proteins Are β-Barrels. [PDF]
MicroPubl BiolThe discovery of Wza, an octomeric helical barrel integral bacterial outer-transmembrane protein, has challenged the widely held understanding that all integral outer-membrane proteins of Gram-negative bacteria are closed β-barrels composed of transmembrane β- strands.
Heido J +4 more
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Frontiers in Chemistry, 2022 Antimicrobial peptides (AMPs) are a unique and diverse group of molecules endowed with a broad spectrum of antibiotics properties that are being considered as new alternative therapeutic agents.
Angela Di Somma +13 more
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Protein-protein interactions and the spatiotemporal dynamics of bacterial outer membrane proteins.
Curr Opin Struct Biol, 2015 It has until recently been unclear whether outer membrane proteins (OMPs) of Gram-negative bacteria are organized or distributed randomly. Studies now suggest promiscuous protein-protein interactions (PPIs) between β-barrel OMPs in Escherichia coli govern their local and global dynamics, engender spatiotemporal patterning of the outer membrane into ...
Kleanthous C, Rassam P, Baumann CG.
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Structural and functional studies of bacterial outer membrane proteins [PDF]
, 2010 This thesis studies two particular bacterial outer membrane proteins called OmpC and Wzi, focusing on their expression, purification, crystallization and X-ray structure determination.
Lou, Hubing
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HELICOBACTER PYLORI OIPA VIRULENCE GENE AS A MOLECULAR MARKER OF SEVERE GASTROPATHIES [PDF]
Arquivos de GastroenterologiaBackground: Helicobacter pylori is an etiologic agent of gastroduodenal diseases. The microorganism, considered a type I carcinogen, affects about 50% of the global population. H.
Diogo Nery MACIEL +4 more
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Subdominant antigens in bacterial vaccines: AM779 is subdominant in the Anaplasma marginale outer membrane vaccine but does not associate with protective immunity. [PDF]
PLoS ONE, 2012 Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial vaccines.
Saleh M Albarrak +8 more
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Mechanisms of Protein Export across the Bacterial Outer Membrane [PDF]
Journal of Bacteriology, 2005 Gram-negative bacteria secrete a wide range of proteins whose functions include biogenesis of organelles, such as pili and flagella; nutrient acquisition; virulence; and efflux of drugs and other toxins. Export of these proteins to the bacterial surface involves transport across the inner membrane (IM), periplasm, and outer membrane (OM) of the cell ...
Maria, Kostakioti +3 more
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Detection of the babA2 adhesin gene in Helicobacter pylori clinical isolates and correlation with upper gastrointestinal diseases [PDF]
Anais da Academia Brasileira de CiênciasHelicobacter pylori is an oncobacteria that infects more than half of the world’s population. Adhesins are virulence factors that are essential for the microorganism to bind to the gastric mucosa, such as the BabA adhesion protein, which is associated ...
DIOGO NERY MACIEL +5 more
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Pattern of amino acid substitutions in transmembrane domains of β-barrel membrane proteins for detecting remote homologs in bacteria and mitochondria. [PDF]
PLoS ONE, 2011 β-barrel membrane proteins play an important role in controlling the exchange and transport of ions and organic molecules across bacterial and mitochondrial outer membranes.
David Jimenez-Morales, Jie Liang
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Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]
, 2007 Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Philippar, Katrin +2 more
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