Results 281 to 290 of about 1,336,409 (334)

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

Advanced Healthcare Materials, EarlyView.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite, Emilie Duthoo, Mathilde Lefevre, Elise Hennebert, Patrick Flammang   +4 more
wiley   +1 more source

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Preparation of Bifunctional Orthosilicophosphate MgO‐CaO‐ZnO‐P2O5‐SiO2 Glasses: in vitro Evaluation of Antibacterial Activity and Osteoblast Gene Expression Behavior

Advanced Healthcare Materials, EarlyView.
Bifunctional ZnO‐containing orthosilicophosphate glasses (SPGs) composed mainly of orthotetrahedral groups with the unique glass network structure without long‐chain units are prepared via melt‐quenching. The glasses exhibit excellent antibacterial activity and upregulate the expression of osteogenic markers by releasing inorganic ions.
Sungho Lee, Hayato Asano, Makoto Sakurai, Takayoshi Nakano, Toshihiro Kasuga   +4 more
wiley   +1 more source

Modulation of the host innate immune and inflammatory response by translocated bacterial proteins. [PDF]

Cell Microbiol, 2015
Asrat S, Davis KM, Isberg RR.
europepmc   +1 more source

Borate‐Ion‐Stimulated Macrophages Promote Osteogenic Differentiation of Mesenchymal Stem Cells

Advanced Healthcare Materials, EarlyView.
The immune responses of mouse macrophages stimulated by borate ions promote the osteogenic differentiation and mineralization of mouse bone marrow–derived mesenchymal stem cells in an ion‐dose‐dependent manner by providing cytokines, including BMP‐2.
Kazumasa Ikedo, Hiroki Hatakeyama, Sayaka Oguri, Akiko Obata, Toshihiro Kasuga   +4 more
wiley   +1 more source

Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review

Advanced Healthcare Materials, EarlyView.
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli, Seshasai Srinivasan, Amin Reza Rajabzadeh   +2 more
wiley   +1 more source

Beyond Bioactive Glass Composition: Using Morphology to Improve in Vitro and in Vivo Performance

Advanced Healthcare Materials, EarlyView.
Bioactive glasses can easily be shaped into granules, spheres, discs, fibers, or three‐dimensional scaffolds. The resulting morphology not only affects handling properties; it has a direct influence on various glass properties, including results of acellular immersion experiments or in vitro studies with cells or bacteria, but also on in vivo ...
Meixin Su, Mert Ergin, Diana Horkavcová, Victoria Horbert, Georg Matziolis, Delia S. Brauer   +5 more
wiley   +1 more source

Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices

Advanced Healthcare Materials, EarlyView.
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco, Zhibing Zhang, Neil M. Eisenstein, Nigel Tai, Liam M. Grover   +4 more
wiley   +1 more source

Co‐Delivery of Ca‐MOF and Mg‐MOF Using Nanoengineered Hydrogels to Promote In Situ Mineralization and Bone Defect Repair: In Vitro and In Vivo Analysis

Advanced Healthcare Materials, EarlyView.
Metal‐organic frameworks (MOFs) have been synthesized using calcium (Ca‐MOF), magnesium (Mg‐MOF), and as hybrids (Ca/Mg‐MOF) for bone healing applications. MOFs are integrated into hydrogel polymer networks for injectable, sprayable, and coating applications.
Cho‐E Choi, Chao Liang, Yasmeen Shamiya, Sang Jin Lee, Arghya Paul   +4 more
wiley   +1 more source

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source