Results 111 to 120 of about 698,346 (166)
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Orthopedic Clinics of North America, 1991
Pathogenic bacteria remain adaptable to an increasingly hostile environment and a wider variety of more potent antibiotics. Organisms not intrinsically prepared for defense have been able to acquire resistance to newer antimicrobial agents. Chromosomal mutations alone cannot account for the rapid emergence and spread of antibiotic resistance.
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Pathogenic bacteria remain adaptable to an increasingly hostile environment and a wider variety of more potent antibiotics. Organisms not intrinsically prepared for defense have been able to acquire resistance to newer antimicrobial agents. Chromosomal mutations alone cannot account for the rapid emergence and spread of antibiotic resistance.
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Bacterial tellurite resistance
Trends in Microbiology, 1999Tellurium compounds are used in several industrial processes, although they are relatively rare in the environment. Genes associated with tellurite resistance (TeR) are found in many pathogenic bacteria. Tellurite can be detoxified through interactions with cellular thiols, such as glutathione, or a methyltransferase-catalyzed reaction, although ...
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Dermatology, 1998
Antibiotics play a major role in acne therapy. Physicians base treatment choices on personal perceptions of efficacy, cost-effectiveness or risk-benefit ratios and rarely take bacterial resistance into account. It is well documented that resistant strains of coagulase-negative staphylococci within the resident skin flora increase in both prevalence and
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Antibiotics play a major role in acne therapy. Physicians base treatment choices on personal perceptions of efficacy, cost-effectiveness or risk-benefit ratios and rarely take bacterial resistance into account. It is well documented that resistant strains of coagulase-negative staphylococci within the resident skin flora increase in both prevalence and
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Bacterial resistance to streptothricins
Journal of Basic Microbiology, 1985AbstractResistance to streptothricin was studied in bacteria with different resistance mechanisms. The laboratory‐induced streptothricin‐resistant mutant E. coli A19 Stcr 2/2/1 showed a high level of cross‐resistance to aminoglycosides and other miscoding inducing antibiotics. In contrast, amino‐glycosid‐resistant E.
I, Haupt, H, Thrum
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BACTERIAL RESISTANCE TO ANTIBIOTICS
Annals of Internal Medicine, 1948Excerpt The development of resistance to the antibiotic drugs is a problem of theoretical interest to the bacteriologist and of practical importance to the clinician.
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Mechanisms of Bacterial Resistance
Pediatric Clinics of North America, 1995Antibiotic resistance is a growing problem in clinical pediatrics. Many of the agents traditionally used to treat pediatric pathogens are becoming less effective because of increasing bacterial resistance. In addition, many more children are immunocompromised because of primary or acquired immunodeficiencies and because of advances in cancer ...
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Bacterial Resistance to Fluoroquinolones
Clinical Infectious Diseases, 1988Fluoroquinolones inhibit bacteria by interacting with the A subunit of DNA gyrase. Resistance to older agents such as nalidixic acid was due to mutations in the gyrA gene. Resistance to the new fluoroquinolones (e.g., norfloxacin, enoxacin, ofloxacin, pefloxacin, and ciprofloxacin) as a consequence of spontaneous single-step mutation occurs at a low ...
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Journal of Chemotherapy, 2009
The emergence of bacterial resistance to antimicrobial agents has caused increasing concern globally. the basis of bacterial resistance to antibiotics is well known, while the nonsusceptibility mechanisms of bacteria to biocides are less well understood. Recently, there is considerable interest in the problems associated with the development and spread
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The emergence of bacterial resistance to antimicrobial agents has caused increasing concern globally. the basis of bacterial resistance to antibiotics is well known, while the nonsusceptibility mechanisms of bacteria to biocides are less well understood. Recently, there is considerable interest in the problems associated with the development and spread
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Overview perspective of bacterial resistance
Expert Opinion on Therapeutic Patents, 2010The rapidly escalating prevalence of antimicrobial resistance is a global concern. This reduced susceptibility to currently available antimicrobial agents coupled with the progressive shortage of newly approved compounds is a worrisome situation.
Guilherme H, Furtado, David P, Nicolau
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Bacterial Resistance to Carbapenems
1995The carbapenems have the broadest spectra of all beta-lactams but resistance still occurs, caused by target modification, impermeability or beta-lactamase production. Target modification or replacement is important in methicillin-resistant staphylococci, E. faecium and some pneumococci.
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