Results 31 to 40 of about 1,259,485 (310)

PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance. [PDF]

open access: yes, 2018
β-lactam antibiotics are excellent drugs for treatment of staphylococcal infections, due to their superior efficacy and safety compared to other drugs.
Chambers, Henry F   +3 more
core   +3 more sources

Formulation of a live bacterial vaccine for stable room temperature storage results in loss of acid, bile and bile salt resistance [PDF]

open access: yes, 2008
Live bacterial vaccines have great promise both as vaccines against enteric pathogens and as heterologous antigen vectors against diverse diseases. Ideally, room temperature stable dry formulations of live bacterial vaccines will allow oral vaccination ...
Edwards, Alexander D.   +1 more
core   +1 more source

Performance of Modified-EUCAST Rapid Direct Antimicrobial Susceptibility Testing on Clinical Urine Samples

open access: yesAnnals of Clinical Microbiology, 2020
배경:소변 검체 배양 후 신속하게 항균제 감수성 결과를 얻는 것은 적절한 항균제로 환자를 치료하기 위하여 중요하다. 본 연구에서는 EUCAST가 제시한 혈액 신속 직접 항균제 감수성 검사법을 뇨 검체에서 적용하여 평가하고자 하였다.방법: 유세포 분석기(Sysmex UF-1000i, Japan)와 그람염색법으로 선별검사 후, 2 × 104 bacteria/ mL 이상의 단일 세균 형태를 갖는 103개의 뇨 검체를 대상으로 하였다. EUCAST 혈액 신속
저스틴 무지라네자   +5 more
doaj   +1 more source

Bacterial resistance to antimicrobial agents and its impact on veterinary and human medicine [PDF]

open access: yes, 2016
Background Antimicrobial resistance has become a major challenge in veterinary medicine, particularly in the context of bacterial pathogens that play a role in both humans and animals.
Aarestrup   +123 more
core   +3 more sources

Multidrug Resistance Pumps as a Keystone of Bacterial Resistance

open access: yesMoscow University Biological Sciences Bulletin, 2022
Antibiotic resistance is a global problem of modern medicine. A harbinger of the onset of the post-antibiotic era is the complexity and high cost of developing new antibiotics, as well as their ineffi ciency due to the rapidly developing resistance of bacteria.
Pavel Nazarov   +2 more
openaire   +2 more sources

Predominance of OXA-48 Carbapenemase-Producing Enterobacterales in a Moroccan Hospital

open access: yesInternational Journal of Microbiology, 2023
Objective. The emergence of carbapenemase-producing Enterobacterales (CPE) is a major concern that is increasingly reported worldwide. Our study aimed at investigating the resistance of CPE isolates in a Moroccan teaching hospital using phenotypic and ...
El Mehdi Belouad   +5 more
doaj   +1 more source

The tomato Prf complex is a molecular trap for bacterial effectors based on Pto transphosphorylation [PDF]

open access: yes, 2013
The bacteria Pseudomonas syringae is a pathogen of many crop species and one of the model pathogens for studying plant and bacterial arms race coevolution.
A Balmuth   +47 more
core   +3 more sources

In Vitro Activity of a Novel Siderophore-Cephalosporin, GT-1 and Serine-Type β-Lactamase Inhibitor, GT-055, against Escherichia coli, Klebsiella pneumoniae and Acinetobacter spp. Panel Strains

open access: yesAntibiotics, 2020
This study investigates GT-1 (also known as LCB10-0200), a novel-siderophore cephalosporin, inhibited multidrug-resistant (MDR) Gram-negative pathogen, via a Trojan horse strategy exploiting iron-uptake systems. We investigated GT-1 activity and the role
Le Phuong Nguyen   +7 more
doaj   +1 more source

Ion mobility mass spectrometry for the study of mycobacterial mycolic acids

open access: yesScientific Reports, 2023
Lipids are highly structurally diverse molecules involved in a wide variety of biological processes. The involvement of lipids is even more pronounced in mycobacteria, including the human pathogen Mycobacterium tuberculosis, which produces a highly ...
Yi Liu   +4 more
doaj   +1 more source

Development of Colonic Organoids Containing Enteric Nerves or Blood Vessels from Human Embryonic Stem Cells

open access: yesCells, 2020
The increased interest in organoid research in recent years has contributed to an improved understanding of diseases that are currently untreatable.
Chul Soon Park   +2 more
doaj   +1 more source

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