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Bacterial Secretion Systems with an Emphasis on the Chlamydial Type III Secretion System [PDF]
Current Issues in Molecular Biology, 2010 Numerous bacterial proteins exert their function outside the prokaryotic cell. To this end, both Gram-negative and Gram-positive bacteria have evolved specialized mechanisms to transport their proteins to the bacterial supernatant or host cell cytoplasm, so called secretion systems.
Beeckman, Delphine Sylvie Anne +1 more
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Frontiers in Microbiology, 2013 Bacterial colonization of biotic or abiotic surfaces results from two quite distinct physiological processes, namely bacterial adhesion and biofilm formation. Broadly speaking, a biofilm is defined as the sessile development of microbial cells.
Caroline eCHAGNOT +4 more
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Frontiers in Microbiology, 2022 The ABC transporter hemolysin B (HlyB) is the key protein of the HlyA secretion system, a paradigm of type 1 secretion systems (T1SS). T1SS catalyze the one-step substrate transport across both membranes of Gram-negative bacteria.
Zohreh Pourhassan N. +5 more
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Bacterial Type IV Secretion Systems: Versatile Virulence Machines [PDF]
Future Microbiology, 2012 Many bacterial pathogens employ multicomponent protein complexes to deliver macromolecules directly into their eukaryotic host cell to promote infection. Some Gram-negative pathogens use a versatile Type IV secretion system (T4SS) that can translocate DNA or proteins into host cells.
Daniel E, Voth +2 more
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Advances in the Assembly Model of Bacterial Type IVB Secretion Systems
Applied Sciences, 2018 Bacterial type IV secretion systems (T4SSs) are related to not only secretion of effector proteins and virulence factors, but also to bacterial conjugation systems that promote bacterial horizontal gene transfer.
Shan Wang +4 more
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The Role of ClpB in Bacterial Stress Responses and Virulence
Frontiers in Molecular Biosciences, 2021 Bacterial survival within a mammalian host is contingent upon sensing environmental perturbations and initiating an appropriate counter-response. To achieve this, sophisticated molecular machineries are used, where bacterial chaperone systems play key ...
Athar Alam +3 more
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A Widespread Bacterial Secretion System with Diverse Substrates
mBio, 2021 The microbial constituency of a host-associated microbiome emerges from a complex physical and chemical interplay of microbial colonization factors, host surface conditions, and host immunological responses. To fill unique niches within a host, bacteria encode surface and secreted proteins that enable interactions with and responses to the host and ...
Alex S. Grossman +3 more
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Characterization of Pseudomonas capsici strains from pepper and tomato
Frontiers in Microbiology, 2023 Disease outbreaks of bacterial leaf spot and blight of pepper and tomato often occur in both transplant- and field-production systems worldwide. In some cases, the outbreaks are caused by novel bacterial species. Characterization of these novel bacterial
Mei Zhao +3 more
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Direct interaction of a chaperone-bound type III secretion substrate with the export gate
Nature Communications, 2022 Recruitment of substrates to virulent bacterial type III secretion systems remains enigmatic. Here, a crystal structure reveals two binding sites between a secretion substrate in complex with its chaperone and the cytosolic domain of the export gate.
Dominic Gilzer +2 more
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Bacterial flagella and type III secretion systems [PDF]
FEMS Microbiology Letters, 2001 Certain classes of pathogenic bacteria secrete virulence proteins in a Sec-independent manner, by a mechanism known as type III secretion. The main body of the export apparatus specific for virulence proteins is identified as a needle complex, which has a similar structural organization to flagella. The two structures share several proteins with highly
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