Results 41 to 50 of about 168,620 (156)
mBio, 2022 Type VIIb secretion systems (T7SSb) were recently proposed to mediate different aspects of Firmicutes physiology, including bacterial pathogenicity and competition. However, their architecture and mechanism of action remain largely obscure.
Matteo Tassinari +10 more
doaj +1 more source
Bacterial type VI secretion system facilitates niche domination [PDF]
Proceedings of the National Academy of Sciences, 2018 Over the last few decades humanity has experienced a series of tremendous technological advances, especially in the realm of basic science. A plethora of new approaches has allowed us to appreciate life in previously unimaginable detail, prompting the realization that life in the microscopic world is not so different from what we can observe with our ...
Drebes Dörr, Natália C. +1 more
openaire +2 more sources
Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach
Frontiers in Cellular and Infection Microbiology, 2018 Pseudomonas aeruginosa is an opportunistic pathogen which uses a number of strategies to cross epithelial and endothelial barriers at cell–cell junctions. In this review, we describe how the coordinated actions of P.
Guillaume Golovkine +2 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2017 Initially identified in pathogenic Gram-negative bacteria, the two-partner secretion (TPS) pathway, also known as Type Vb secretion, mediates the translocation across the outer membrane of large effector proteins involved in interactions between these ...
Jeremy Guérin +4 more
doaj +1 more source
Signal peptides for recombinant protein secretion in bacterial expression systems
Microbial Cell Factories, 2018 The secretion of biotechnologically or pharmaceutically relevant recombinant proteins into the culture supernatant of a bacterial expression host greatly facilitates their downstream processing and significantly reduces the production costs.
Roland Freudl
doaj +1 more source
Comparative genomics and genome biology of Campylobacter showae
Emerging Microbes and Infections, 2019 Campylobacter showae a bacterium historically linked to gingivitis and periodontitis, has recently been associated with inflammatory bowel disease and colorectal cancer. Our aim was to generate genome sequences for new clinical C.
Tiffany Hsu +13 more
doaj +1 more source
Computational and experimental analysis of the secretome of Methylococcus capsulatus (Bath). [PDF]
PLoS ONE, 2014 The Gram-negative methanotroph Methylococcus capsulatus (Bath) was recently demonstrated to abrogate inflammation in a murine model of inflammatory bowel disease, suggesting interactions with cells involved in maintaining mucosal homeostasis and ...
Stine Indrelid +4 more
doaj +1 more source
Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System
mBio, 2022 Bacterial type VIIb secretion systems (T7SSb) are multisubunit integral membrane protein complexes found in Firmicutes that play a role in both bacterial competition and virulence by secreting toxic effector proteins.
Timothy A. Klein +7 more
doaj +1 more source
Bacterial Type II Secretion System and Its Mitochondrial Counterpart
mBio, 2023 Over the billions of years that bacteria have been around, they have evolved several sophisticated protein secretion nanomachines to deliver toxins, hydrolytic enzymes, and effector proteins into their environments. Of these, the type II secretion system (T2SS) is used by Gram-negative bacteria to export a wide range of folded proteins from the ...
Shaliutina-Loginova, Anna +2 more
openaire +3 more sources
Delivery of Toxins and Effectors by Bacterial Membrane Vesicles
Toxins, 2021 Pathogenic bacteria interact with cells of their host via many factors. The surface components, i.e., adhesins, lipoproteins, LPS and glycoconjugates, are particularly important in the initial stages of colonization.
Adrian Macion +2 more
doaj +1 more source