Specific immune response in the respiratory tract after administration of an oral polyvalent bacterial vaccine [PDF]
Robert Clancy+3 more
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B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong+16 more
wiley +1 more source
Effect of the mixed bacterial vaccine on the immune response of patients with non-small cell lung cancer and refractory malignancies [PDF]
Rita Axelrod+4 more
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Bacterial Foreignization Nanosystem Elicits Multi‐Phenotypic T Cells for Antitumor Immunity
In this study, a comprehensive strategy for tumor immunogenicity reshaping is implemented, in which all adjuvanticity, antigenicity, and reactogenicity of tumor cells are highly improved by an engineered bacterial nanosystem through a selective membrane fusion process. The resulting foreignized tumor cells evoke potent innate immune responses, inducing
Wan‐Ru Zhuang+10 more
wiley +1 more source
Vaccines '87: Modern Approaches to New Vaccines. Prevention of AIDS and Other Viral, Bacterial and Parasitic Diseases. Edited by R. M. Chanock, R. A. Lerner, F. Brown and H. Ginsberg. Cold Spring Harbor: Cold Spring Harbor Laboratory, New York. 1987. 461 pages. Paper, $95.00. ISBN 0 87969 302 9. [PDF]
Robert G. Ridley
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In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao+13 more
wiley +1 more source
Vaccines '88: New Chemicals and Genetic Approaches to Vaccination. Prevention of AIDS and other viral, bacterial and parasitic diseases. Edited by H. Ginsberg, F. Brown, R. A. Lerner and R. M. Channock. New York: Cold Spring Harbor Labortory. 1988. 396 pages. Paper $9500. ISBN 0 87969 210 X. [PDF]
Robert G. Ridley
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Engineered antibody‐like proteins block the SARS‐CoV‐2 spike protein from binding to host receptors and suppress immune overactivation through an MBL‐based scaffold. These dual‐function proteins effectively alleviate inflammation, complement activation, and lung injury, offering a promising therapeutic strategy against severe COVID‐19 and its ...
Yizhuo Wang+7 more
wiley +1 more source
Salmonella is a significant zoonotic foodborne pathogen, and the global spread of multidrug-resistant (MDR) strains poses substantial challenges, necessitating alternatives to antibiotics.
Abubakar Siddique+9 more
doaj +1 more source
Indirect measurement of intestinal immune responses to an orally administered attenuated bacterial vaccine [PDF]
Bruce D. Forrest
openalex +1 more source