Results 141 to 150 of about 213,855 (329)

The neglected model validation of antimicrobial resistance transmission models – a systematic review

Antimicrobial Resistance and Infection Control
Background In the fight against antimicrobial resistance, mathematical transmission models have been shown as a valuable tool to guide intervention strategies in public health.
Maja L. Brinch, Andrea Palladino, Jeroen Geurtsen, Thierry Van Effelterre, Lorenzo Argante, Michael J. McConnell, Lene Christiansen, Michelle A. Pihl, Natasja K. Lund, Tine Hald   +9 more
doaj   +1 more source

Supplementary figures 1-2 from Preclinical Development of a WT1 Oral Cancer Vaccine Using a Bacterial Vector to Treat Castration-Resistant Prostate Cancer

, 2023
Koichi Kitagawa, Reina Gonoi, Maho Tatsumi, Masahide Kadowaki, Takane Katayama, Yoshiko Hashii, Masato Fujisawa, Toshiro Shirakawa   +7 more
openalex   +1 more source

Digital Point‐of‐Care Testing Device Based on Bioluminescent Pyrophosphate in Real‐Time and Recombinase‐aid Amplification

Advanced Intelligent Systems, EarlyView.
A point‐of‐care testing method based on solvent‐responsive magnetic beads suitable for large‐area diagnosis and mutation screening in remote areas was developed to detect it by combining bioluminescenct pyrophosphate in real‐time technology and recombinase‐aid amplification technology.
Zhongjie Fei, Juan Bai, Liwei Xu, Siyi Wang, Pengfeng Xiao, Dongrui Zhou, Guanxiong Liu, Rongbin Wei, Ping Jiang   +8 more
wiley   +1 more source

Establishment of a biosafe murine model of skeletal tuberculosis using Mycobacterium smegmatis

Animal Models and Experimental Medicine, EarlyView.
This study developed a biosafe, accessible, and versatile murine model of bone TB using Mycobacterium smegmatis, a fast‐growing, nonpathogenic mycobacterial species with high genomic homology to Mycobacterium tuberculosis. Three infection routes—subperiosteal calvarial injection, intratibial injection, and intracardiac (left ventricular) inoculation ...
Yewei Jia, Yuhuai Guo, Yusheng Yang, Jie Zhang, Ziyang Zhang, Ying Qu, Jiulin Tan, Jie Shen, Nathachit Limjunyawong, Jianzhong Xu, Zehua Zhang, Fei Luo, Ce Dou   +12 more
wiley   +1 more source

Transient comparison of techniques to counter multi-drug resistant bacteria: prime modules in curation of bacterial infections

Frontiers in Antibiotics
Multidrug-resistant organisms are bacteria that are no longer controlled or killed by specific drugs. One of two methods causes bacteria multidrug resistance (MDR); first, these bacteria may disguise multiple cell genes coding for drug resistance to a ...
Muhammad Naveed, Muhammad Waseem, Izma Mahkdoom, Nouman Ali, Farrukh Asif, Jawad ul Hassan, Hamza Jamil   +6 more
doaj   +1 more source

Development of a multicomponentStaphylococcus aureusvaccine designed to counter multiple bacterial virulence factors [PDF]

, 2012
Annaliesa S. Anderson, Alita A. Miller, Robert G. K. Donald, Ingrid L. Scully, Jasdeep S. Nanra, David Cooper, Kathrin U. Jansen   +6 more
openalex   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source

Computational approaches to identify common subunit vaccine candidates against bacterial meningitis [PDF]

, 2013
Manne Munikumar, I Vani Priyadarshini, Dibyabhaba Pradhan, Amineni Umamaheswari, B Vengamma   +4 more
openalex   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng, Juping Sun, Junyu Liu, Yuqi Zhang, Wanwan Liu, Xiaobin Li, Han Wu, Juan Li, Jisong Zhang, Chanyuan Jin, Can Yang Zhang   +10 more
wiley   +1 more source