Results 121 to 130 of about 1,232,742 (295)
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
, 2019 The dataset (Vaccines) contains background subtracted frequencies of CD4 and CD8 T cells producing a combination of IFNγ, IL-2, TNF and IL-17 in response to stimulation by vaccine-specific antigens for the vaccines included in the paper "A head-to-head ...
Miguel Julio Rodo (5561078) +6 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani +4 more
wiley +1 more source
Разработка и регистрация лекарственных средств, 2019 The key areas of focus of the WНO on the question of immunization and vaccines including anti-influenza vaccines are generalized. Domestic market of anti-influenza vaccines are analyzed. It is established, that Russian Federation is active participant of
V. P. Trukhin +4 more
doaj
An investigation of novel DNA based vaccines for protection against Brucellosis [PDF]
This thesis describes design, construction and evaluation in a BALB/c mouse model, for five novel Brucella specific DNA vaccines. Brucellosis is worldwide zoonosis of economic significance that poses a significant threat to both animal and human health ...
Commander, Nicola Jane
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British Educational Research Journal, EarlyView.Abstract In this paper, we explore how neurodivergent ways of being in early education are often gendered. The intersectionalities of gender and neurodivergence often lead to fixed expectations that perpetuate binary interpretations, pathologisations, missed diagnoses and a lack of curated support.
Ruth Churchill Dower, Hannah Hogarth
wiley +1 more source
, 1998 Vaccines have proven to be the most successful medical intervention of human morbidity and mortality. Bacterial vaccines have resulted in the marked decrease in the incidence of human infections such as tetanus,diphteria and whooping cough.
Subramaniam, Geetha
core
Live bacterial vaccines – a review and identification of potential hazards
, 2006 The use of live bacteria to induce an immune response to itself or to a carried vaccine component is an attractive vaccine strategy. Advantages of live bacterial vaccines include their mimicry of a natural infection, intrinsic adjuvant properties and ...
Ann Detmer +3 more
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Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines
Biotechnology and Bioengineering, EarlyView.ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt +3 more
wiley +1 more source
Opening the OPK Assay Gatekeeper: Harnessing Multi-Modal Protection by Pneumococcal Vaccines
, 2019 Pneumococcal vaccine development is driven by the achievement of high activity in a single gatekeeper assay: the bacterial opsonophagocytic killing (OPK) assay.
Beth Mann +3 more
core +1 more source