Results 161 to 170 of about 94,986 (281)

Recent Advances in Bioconjugate Vaccine Development

Vaccines
Glycoconjugate vaccines, consisting of a protein component covalently linked to a glycan antigen, have led to a significant reduction in the global occurrence of bacterial meningitis and pneumonia. They provide robust, lasting immunity in all age groups.
Brendan W. Wren, Catherine L. Hall, Vanessa S. Terra, Mark A. Harrison, Elizabeth Atkins, Fauzy Nasher, Ian J. Passmore   +6 more
doaj   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source

Cancer Vaccine Design: A Novel Bacterial Adjuvant for Peptide-Specific CTL Induction [PDF]

, 2001
Isabelle Miconnet, Isabelle Coste, Friedrich Beermann, Jean‐François Haeuw, Jean‐Charles Cerottini, Jean‐Yves Bonnefoy, Pedro Romero, Toufic Renno   +7 more
openalex   +1 more source

Novel Swelling‐Lytic Cell Death Triggered by Cargo‐Free Ionizable Lipid Nanoparticles

Advanced Science, EarlyView.
A cargo‐free ionizable lipid nanoparticles (ipLNP) is found to induce broad swelling‐lytic cell death across multiple cell types. Cell death may be associated with lysosome membrane destabilization, involving ROS increase, lipid peroxidation, and GSDME cleavage.
Junjun Wu, Zhennan Zhao, Hongsheng Wu, Sihuang Lin, Lin Huang, Guanjie Chen, Yi Yang, Hong Wang, Huijie Yan, Yonghui Shi, Liuyu Zhu, Guosheng Hu, Liling Zheng, Songying Ouyang   +13 more
wiley   +1 more source

Polymerisation‐Induced Self‐Assembly on Planar Surfaces: A New Approach for Controlling Surface Topography and Modulating Material‐Bio Interactions

Angewandte Chemie, EarlyView.
This work investigates surface‐initiated photopolymerisation‐induced self‐assembly (surface PISA) as an innovative strategy for directing nanostructure formation on planar surfaces, providing a new approach to tailoring material surface topography and achieving enhanced antifouling and antibacterial surface properties.
Xin Xu, Jia‐Qi Xu, You‐Liang Zhu, Yixin Chang, Yuhao Zhang, Hui Peng, Zhong‐Yuan Lu, Andrew Whittaker, Changkui Fu   +8 more
wiley   +2 more sources

Bacterial Vaccines

, 2014
Chorobik, Paulina, Bereta, Joanna
openaire   +2 more sources

Bioinformatics: Use in Bacterial Vaccine Discovery [PDF]

, 2001
Robert J. Zagursky, David H. Russell
openalex   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Synthesis of Chirally Chimeric Protein Nanoparticle Vaccines via Mirror‐Image Spy Chemistry

Angewandte Chemie, EarlyView.
This study illustrates a versatile strategy for creating chirally chimeric protein constructs by merging natural‐chirality (L‐) and mirror‐image (D‐) protein motifs through a combination of L‐sortase‐mediated transpeptidation and D‐SpyStapler‐mediated ligation.
Songzi Kou, Chenbo Sun, Weitao Chen, Hanyu Gao, Fei Sun   +4 more
wiley   +2 more sources

Meningoencefalitis bacterianas en Cuba

Revista Cubana de Higiene y Epidemiología
Se describieron algunos aspectos epidemiológicos de las meningoencefalitis bacterianas (MEB) en Cuba entre 1993 y 1998 según datos disponibles en el registro de enfermedades de Declaración Obligatoria del Ministerio de Salud Pública.
Félix Orlando Dickinson Meneses, Antonio Esteban Pérez Rodríguez   +1 more
doaj