Results 171 to 180 of about 112,154 (311)

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

open access: yesChemistry &Biodiversity, EarlyView.
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang   +8 more
wiley   +1 more source

Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential

open access: yesChemBioEng Reviews, EarlyView.
This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona   +2 more
wiley   +1 more source

Cold‐Adapted Lipid A from Polaribacter sp. SM1127: A Study of Structural Heterogeneity and Immunostimulatory properties

open access: yesChemBioChem, Accepted Article.
Polaribacter sp. SM1127, a cold‐adapted marine Gram‐negative bacterium isolated from Laminaria in Arctic waters, plays a crucial role in nutrient cycling and biopolymer degradation in cold environments. Additionally, its exopolysaccharide (EPS) exhibits promising biotechnological potential, including antioxidant and wound‐healing properties. This study
Roberta Cirella   +9 more
wiley   +1 more source

Vaccines against human enteric bacterial pathogens [PDF]

open access: bronze, 2002
Gordon Dougan, Alan Huett, Simon Clare
openalex   +1 more source

Profiling Serine Hydrolases in the Leishmania Host‐Pathogen Interactome Using Cell‐Permeable Activity‐Based Fluorophosphonate Probes

open access: yesChemBioChem, Accepted Article.
Leishmaniasis, a vector borne neglected tropical disease, caused by the protozoan parasite Leishmania, is a major global public health challenge with millions of new cases annually. Treatment of leishmaniasis is difficult for many reasons including a multiple life‐cycle stages, involving both an infective insect vector form, the promastigote, and a ...
Jaime A. Isern   +7 more
wiley   +1 more source

Synthesis of a Set of Staphylococcus Aureus Capsular Polysaccharide Type 1 Oligosaccharides Carrying Taurine Esters

open access: yesChemistry – A European Journal, EarlyView.
Staphylococcus aureus serotype 1 is a highly virulent pathogen and the capsular polysaccharide (CP1) has been shown to play an important role in virulence and be a target for opsonic antibodies. We here describe the synthesis of a set of CP1 oligosaccharides, varying in length and with different taurination patterns. Abstract Staphylococcus aureus is a
Kitt Emilie Østerlid   +4 more
wiley   +1 more source

Mechanistic research holds promise for bacterial vaccines and phage therapies for Pseudomonas aeruginosa. [PDF]

open access: yesDrug Des Devel Ther, 2019
Hoggarth A   +7 more
europepmc   +1 more source

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