Results 191 to 200 of about 129,578 (294)

Nutritional properties, traditional uses and potential new applications for the sotol plant (Asparagaceae, Convallarioideae): A review

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Sotol (Dasylirion spp.) is a resilient desert plant that sustains ecosystems, cultures and livelihoods in Chihuahua Desert. Our review highlights its nutritional properties, traditional uses and potential new applications in food, pharmaceuticals, renewable energy and water remediation. By synthesizing evidence across disciplines, we show how sotol can
Dámaris Leopoldina Ojeda Barrios   +7 more
wiley   +1 more source

A new perspective on cancer treatment: the interaction and application prospect between ICIs and radiotherapy

open access: yesPrecision Radiation Oncology, EarlyView.
The combination of immune checkpoint inhibitors (ICIs) and radiotherapy synergistically enhances efficacy through an “antigen release‐immune activation” closed‐loop mechanism, significantly improving outcomes in solid tumors (e.g., lung cancer, melanoma).
Guiling Song   +5 more
wiley   +1 more source

Avaliação da proteção conferida pela vacina antimeningocócica BC no Estado de Santa Catarina, Brazil, 1990/92

open access: yesRevista de Saúde Pública
São apresentados os resultados da avaliação da vacina antimeningocócica BC de procedência cubana realizada com dados da vigilância epidemiológica de meningites do Estado de Santa Catarina, Brasil, dos anos de 1990-92. A eficácia para os casos confirmados
Eduardo de A. Costa   +2 more
doaj  

Camels as a Climate‐Resilient Linchpin for Sustainable Development in Global Drylands

open access: yesSustainable Development, EarlyView.
ABSTRACT Camels represent a significant, yet underutilized, asset for advancing integrated sustainable development in the world's expanding drylands. Previous reviews have examined camels' physiology, milk composition, or pastoral systems in isolation; this review examines their potential as a climate‐resilient linchpin for food systems by synthesizing
Ayana Angassa   +2 more
wiley   +1 more source

RNA‐DNA Fusomer Fibers With Customizable Physicochemical, Mechanical, and Biological Properties for Next‐Generation Therapeutics

open access: yesSmall, EarlyView.
ABSTRACT We introduce RNA‐DNA fusomers, a new class of chemically synthesized oligonucleotides that combine the versatile properties of RNA and DNA within a single sequence and self‐assemble into higher‐order functional structures via a simple one‐pot annealing reaction.
Yasmine Radwan   +21 more
wiley   +1 more source

Stepwise mitochondria‐targeted photodynamic immunotherapy enabled by an outer membrane vesicles‐based nanoplatform for synergistic tumor ablation and immune reprogramming

open access: yesSmart Molecules, EarlyView.
We constructed a novel excellent photodynamic drug without heavy atoms based on the conventional BODIPY photosensitizer, and then obtained a photodynamic vesicle with efficient tumor targeting (BDPM@OMVs) by bacterial extravasation. Multiple reactive oxygen species were efficiently generated under light irradiation, and the spontaneous elimination of ...
Xiang Cheng   +11 more
wiley   +1 more source

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

open access: yesVeterinary Record, EarlyView.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson   +2 more
wiley   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

open access: yesVIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu   +10 more
wiley   +1 more source

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