Results 231 to 240 of about 94,986 (281)

Exploring the Potential and Advancements of Circular RNA Therapeutics

open access: yesExploration, EarlyView.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang   +6 more
wiley   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

A Multifaceted Review on Neodiosmin In Planta Distribution, (Bio)synthesis, Food and Health Effects

open access: yesFuture Postharvest and Food, EarlyView.
ABSTRACT Neodiosmin (NEO) is a major glycosylated flavone that is derived from the bitter flavanone neo‐hesperidin in citrus fruits including orange, lime, and lemon. One of the most important features of NEO is that it exerts a notable debittering effect on plant flavonoids justifying its wide use as a food additive.
Yuxuan Zhao   +4 more
wiley   +1 more source

Prevalence and Genotype Distribution of Sapovirus in China: A Systematic Review and Meta‐Analysis

open access: yesGlobal Challenges, EarlyView.
This review highlights a distinct age‐related trend in Sapovirus (SaV) prevalence in China, peaking among kindergarten children and adults. These results not only enhance the understanding of SaV's epidemiology but also provide a robust foundation for estimating disease burden and informing the development of targeted vaccines and public health ...
Zhao Gao   +6 more
wiley   +1 more source

Bacterially Produced Recombinant Influenza Vaccines Based on Virus-Like Particles

open access: gold, 2013
Andrea Jegerlehner   +6 more
openalex   +2 more sources

Effects of SADS‐CoV accessory proteins NS3a, NS7a, and NS7b on viral pathogenicity: A multi‐omics investigation

open access: yesiMetaOmics, EarlyView.
This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan   +7 more
wiley   +1 more source

Russian vaccines against especially dangerous bacterial pathogens

open access: gold, 2014
Valentina Feodorova   +3 more
openalex   +1 more source

Multi‐omics analysis of gut‐organ axes reveals the high‐altitude adaptation in Tibetan chicken

open access: yesiMetaOmics, EarlyView.
The Qinghai‐Tibet Plateau is an extreme ecosystem subject to special climatic conditions that require unique adaptations for its inhabiting organisms. In addition to genetic characteristics, the gut microbiota of animals can regulate the environmental adaptation of their hosts through various gut–organ axes.
Tao Zeng   +15 more
wiley   +1 more source

Gut microbiota and tuberculosis

open access: yesiMeta, EarlyView.
This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu   +39 more
wiley   +1 more source

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