Andrology, EarlyView.ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam +7 more
wiley +1 more source
Targeted pneumococcal conjugate vaccination strategies for high-risk children. [PDF]
Hum Vaccin ImmunotherHart J +4 more
europepmc +1 more source
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
Acta Paediatrica, EarlyView.ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Immunoprophylactic potential against pneumonia caused by indigenous isolates of Klebsiella pneumoniae and Streptococcus pneumoniae in experimental mice. [PDF]
Sci RepWaqar I +4 more
europepmc +1 more source
Acta Paediatrica, EarlyView.ABSTRACT Aim The aim of this study was to investigate the possible source of laboratory‐confirmed pertussis in infants under 6 months of age. Methods This nationwide prospective study was based on laboratory‐confirmed cases reported in the enhanced pertussis surveillance in Sweden from 2009 to 2015. The parents or carers of 345 infants were interviewed
Bernice Aronsson +4 more
wiley +1 more source
Immune Protection Effect of an OmpC-Recombinant T4 Bacteriophage Vaccine Against Infection Caused by Extraintestinal Pathogenic <i>Escherichia coli</i> in Mice. [PDF]
Vaccines (Basel)Zong X +10 more
europepmc +1 more source
Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe
Acta Paediatrica, EarlyView.ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner +2 more
wiley +1 more source
Prevention of neuroinfectious-diseases: high impact of vaccination programs - but the potential is not maxed out yet. [PDF]
Neurol Res PractKlein M +6 more
europepmc +1 more source
Investigation of Correlates of Protection Against Gonococcal Infection by Comparative Immunoprofiling of Responses in Experimental and Clinical Studies. [PDF]
J Infect DisMcKeand SA +10 more
europepmc +1 more source
Acta Paediatrica, EarlyView.ABSTRACT Aim Countries with varicella immunisation programmes have seen major reductions in disease burden. While two‐dose schedules are now universally adopted, dosing ages vary, and some countries initially include catch‐up vaccination of older children to speed impact. This modelling study assessed three two‐dose schedules in the Swedish setting (1)
Gianpaolo Scalia Tomba +6 more
wiley +1 more source