Results 241 to 250 of about 112,154 (311)

In Situ Gels for Nasal Delivery: Formulation, Characterization and Applications

Macromolecular Materials and Engineering, EarlyView.
Drug delivery through the nasal route offers many advantages, but is hampered by a number of challenges, such as the short drug retention time caused by mucociliary clearance. In situ forming gels, which undergo a sol‐to‐gel transition with specific triggers at the site of action, present real opportunities in this field.
Li Qian, Michael T. Cook, Cécile A. Dreiss   +2 more
wiley   +1 more source

A polyvalent vaccine for selectively killing tumor-associated bacteria to prevent cancer metastasis. [PDF]

Sci Adv
Kang Z, Chen L, Li P, Zheng Z, Shen J, Xiao Z, Miao Y, Yang Y, Chen Q.   +8 more
europepmc   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Editorial: The World Health Organization (WHO) Updated List of Emerging and Potentially Pandemic Pathogens Includes Yersinia pestis as Plague Vaccines Await Clinical Trials. [PDF]

Med Sci Monit
Parums DV.
europepmc   +1 more source

Identification of a phenyl ester covalent inhibitor of caseinolytic protease and analysis of the ClpP1P2 inhibition in mycobacteria

mLife, EarlyView.
Abstract The caseinolytic protease complex ClpP1P2 is crucial for protein homeostasis in mycobacteria and stress response and virulence of the pathogens. Its role as a potential drug target for combating tuberculosis (TB) has just begun to be substantiated in drug discovery research.
Genhui Xiao, Yumeng Cui, Liangliang Zhou, Chuya Niu, Bing Wang, Jinglan Wang, Shaoyang Zhou, Miaomiao Pan, Chi Kin Chan, Yan Xia, Lan Xu, Yu Lu, Shawn Chen   +12 more
wiley   +1 more source

First-ever ASM Global Research Symposium on Microbes in Human Health in Tsinghua, Beijing, China. [PDF]

mSphere
Luo S, Wang Y-T.
europepmc   +1 more source

The Antiviral Activity of Polyphenols

Molecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard, Alban Piotrowsky, Christian Leischner, Katja Detert, Sascha Venturelli, Luigi Marongiu   +5 more
wiley   +1 more source

Bacterially Produced Recombinant Influenza Vaccines Based on Virus-Like Particles

, 2013
Andrea Jegerlehner, Franziska Zabel, Alice Langer, Klaus Dietmeier, Gary T. Jennings, Philippe Saudan, Martin F. Bachmann   +6 more
openalex   +2 more sources

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

Pediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao, Zhongying Yang, Yu He, Jianhua Wei, Luo Ren, Enmei Liu, Na Zang   +6 more
wiley   +1 more source

A Narrative Review of Periodontal Vaccines: Hope or Hype? [PDF]

Cureus
Patel P, Patel B, Vyas SD, Patel MS, Hirani T, Haque M, Kumar S.   +6 more
europepmc   +1 more source