Results 131 to 140 of about 101,641 (219)

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

Histotripsy-Induced Bactericidal Activity Correlates to Size of Cavitation Cloud In Vitro. [PDF]

IEEE Trans Ultrason Ferroelectr Freq Control
Ambekar PA, Wang YN, Khokhlova TD, Thomas GPL, Rosnitskiy PB, Contreras K, Leotta DF, Maxwell AD, Bruce M, Pierson S, Totten S, Kumar YN, Thiel J, Chan K, Liles WC, Dellinger EP, Adedipe A, Monsky WL, Matula TJ.   +18 more
europepmc   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Identification and analysis of the crucial holin domain and sites and the bactericidal activity of a holin-endolysin lysis cassette from phage PZL-Ah152 against <i>Aeromonas hydrophila</i>. [PDF]

J Virol
Feng C, Cheng Y, Liang S, Liang R, Yu J, Wang S, Guo H, Shan X, Zhang D, Qian A, Sun W, Zhang L.   +11 more
europepmc   +1 more source

Bactericidal activity of amoxicillin

The Japanese Journal of Antibiotics, 1979
KAMIMURA, TOSHIAKI, OKADA, NAOHIKO, MATSUMOTO, YOSHIMI, NISHIDA, MINORU   +3 more
openaire   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Neutrophil extracellular traps have active DNAzymes that promote bactericidal activity. [PDF]

Nucleic Acids Res
Ku TH, Ram-Mohan N, Zudock EJ, Abe R, Yang S.   +4 more
europepmc   +1 more source

Bactericidal Activity report

The Bactericidal activity Report will describe the methodology used and the results of two-by-two drug combinations by short murine experiments.
openaire   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

A multifunctional self-assembled hydrogel with bactericidal activity and macrophage metabolic reprogramming for diabetic bone defect repair. [PDF]

Mater Today Bio
Wang L, Wu Z, Chen X, Bai J, Li W, Ge G, Zhang W, Li W, Qin Y, Zhao G, Wang Y, Pan G, Xu Y, Geng D.   +13 more
europepmc   +1 more source