Results 31 to 40 of about 201,125 (313)

Salmonella Typhi Bactericidal Antibodies Reduce Disease Severity but Do Not Protect against Typhoid Fever in a Controlled Human Infection Model

Frontiers in Immunology, 2018
Effective vaccines against Salmonella Typhi, a major cause of febrile illness in tropical regions, can have a significant effect as a disease control measure. Earlier work has shown that immunization with either of two Salmonella Typhi vaccines, licensed
Helene B. Juel, Helene B. Juel, Helena B. Thomaides-Brears, Thomas C. Darton, Thomas C. Darton, Claire Jones, Elizabeth Jones, Sonu Shrestha, Rebecca Sie, Andrew Eustace, Ushma Galal, Prathiba Kurupati, Tan T. Van, Nga T. V. Thieu, Stephen Baker, Stephen Baker, Stephen Baker, Christoph J. Blohmke, Andrew J. Pollard   +18 more
doaj   +1 more source

Severe bloodstream infection due to KPC-producer e coli in a renal transplant recipient treated with the double-carbapenem regimen and analysis of in vitro synergy testing a case report [PDF]

, 2016
Transplant recipients are at high risk of infections caused by multidrug resistant microorganisms. Due to the limited thera- peutic options, innovative antimicrobial combinations against carbape- nem-resistant Enterobacteriaceae causing severe infections
CIPOLLA, ALESSIA, D'ABRAMO, ALESSANDRA, DE ANGELIS, Massimiliano, Favaro, Marco, Ferretti, Giancarlo, GIZZI, FRANCESCA, IANNETTA, MARCO, MASCELLINO, Maria Teresa, MASTROIANNI, Claudio Maria, OLIVA, ALESSANDRA, RUSSO, Gianluca, VULLO, Vincenzo   +11 more
core   +1 more source

Serum bactericidal activity against Legionella pneumophila [PDF]

Journal of Clinical Microbiology, 1985
Two strains of Legionella pneumophila serogroup 1 (UH1 and RH1) were incubated in fresh human serum. The UH1 strain was serum resistant, whereas the RH1 strain was serum susceptible. The bactericidal activity of fresh serum was abrogated by heating. Serum resistance of L. pneumophila strains may correlate with increased virulence.
J F, Plouffe, M F, Para, K A, Fuller
openaire   +2 more sources

The stability of complement-mediated bactericidal activity in human serum against Salmonella.

PLoS ONE, 2012
The complement cascade includes heat-labile proteins and care is required when handling serum in order to preserve its functional integrity. We have previously used a whole human serum bactericidal assay to show that antibody and an intact complement ...
Colette M O'Shaughnessy, Adam F Cunningham, Calman A Maclennan   +2 more
doaj   +1 more source

Fungicidal and bactericidal activity of alkyl-substituting polyetherguanidines

Біологічні студії, 2020
Background. Polyhexamethylene guanidines are widely used as biocides and disinfectants due to the wide range of their antimicrobial activity against Gram-positive and Gram-negative bacteria, viruses, fungi, and molds.
M. Ya. Vortman, Yu. B. Pysmenna, A. V. Rudenko, V. V. Tretyak, V. N. Lemeshko, V. V. Shevchenko   +5 more
doaj   +1 more source

Bactericidal action of photogenerated singlet oxygen from photosensitizers used in plaque disclosing agents. [PDF]

PLoS ONE, 2012
BACKGROUND: Photodynamic therapy (PDT) has been suggested as an efficient clinical approach for the treatment of dental plaque in the field of dental care.
Kirika Ishiyama, Keisuke Nakamura, Hiroyo Ikai, Taro Kanno, Masahiro Kohno, Keiichi Sasaki, Yoshimi Niwano   +6 more
doaj   +1 more source

Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect [PDF]

, 2007
Antisense agents that target growth-essential genes display surprisingly potent bactericidal properties. In particular, peptide nucleic acid (PNA) and phosphorodiamidate morpholino oligomers linked to cationic carrier peptides are effective in time kill ...
Behmanesh, Mehrdad, Dryselius, Rikard, Faridani, Omid R, Ganyu, Anita, Goh, Shan, Good, Liam, Klok, Erik Jan, Nikravesh, Abbas, Sadeghizadeh, Majid, Zain, Rula   +9 more
core   +2 more sources

Harnessing a T1 Phage-Derived Spanin for Developing Phage-Based Antimicrobial Development

BioDesign Research
The global increase in the prevalence of drug-resistant bacteria has necessitated the development of alternative treatments that do not rely on conventional antimicrobial agents.
Wakana Yamashita, Shinjiro Ojima, Azumi Tamura, Aa Haeruman Azam, Kohei Kondo, Zhang Yuancheng, Longzhu Cui, Masaki Shintani, Masato Suzuki, Yoshimasa Takahashi, Koichi Watashi, Satoshi Tsuneda, Kotaro Kiga   +12 more
doaj   +1 more source

Induction of bactericidal activity by degradable implants

Гений oртопедии, 2023
The development of biodegradable implants with bioactive properties is a promising direction. The purpose of this study was to evaluate the in vitro bactericidal activity of implants made from a degradable material polycaprolactone (PCL) impregnated ...
Arnold V. Popkov, Natalia A. Kononovich, Dmitry A. Popkov, Natalia V. Godovykh, Sergei I. Tverdokhlebov, Evgeny N. Bolbasov, Maxim V. Stogov, Elena A. Kireeva, Elena N. Gorbach, Yury Yu. Litvinov   +9 more
doaj   +1 more source

Bactericidal Activity of Lipid-Shelled Nitric Oxide-Loaded Microbubbles

Frontiers in Pharmacology, 2020
The global pandemic of antibiotic resistance is an ever-burgeoning public health challenge, motivating the development of adjunct bactericidal therapies. Nitric oxide (NO) is a potent bioactive gas that induces a variety of therapeutic effects, including
Maxime Lafond, Himanshu Shekhar, Warunya Panmanee, Sydney D. Collins, Arunkumar Palaniappan, Cameron T. McDaniel, Daniel J. Hassett, Christy K. Holland, Christy K. Holland   +8 more
doaj   +1 more source