Results 21 to 30 of about 109,795 (265)

Cefotaxime: rate of bacterial killing and interactions with serum and leukocyte activity.

open access: yesActa Médica Portuguesa, 1983
Cefotaxime (HR 756) was compared with cefazolin and cephaloridine with regard to the rate of bacterial killing and to the influence on the bactericidal activity of human serum and polyrnorphonuclear leukocytes.
Giuliana Gialdroni Grassi   +2 more
doaj   +1 more source

Salmonella Typhi Bactericidal Antibodies Reduce Disease Severity but Do Not Protect against Typhoid Fever in a Controlled Human Infection Model

open access: yesFrontiers in Immunology, 2018
Effective vaccines against Salmonella Typhi, a major cause of febrile illness in tropical regions, can have a significant effect as a disease control measure. Earlier work has shown that immunization with either of two Salmonella Typhi vaccines, licensed
Helene B. Juel   +18 more
doaj   +1 more source

In Vitro Bactericidal Activity of a Neomycin-Polymyxin B-Nystatin Combination Compared to Metronidazole and Clindamycin Against the Main Bacteria Involved in Bacterial Vaginosis and Aerobic Vaginitis

open access: yesPharmaceuticals
Background/Objectives: Aerobic vaginitis (AV) and bacterial vaginosis (BV) are vaginal infections requiring the fast elimination of pathogens. The frequent confusion of these infections may justify the use of a rapidly acting broad-spectrum antibiotic ...
Catherine Feuillolay   +5 more
doaj   +1 more source

The stability of complement-mediated bactericidal activity in human serum against Salmonella.

open access: yesPLoS ONE, 2012
The complement cascade includes heat-labile proteins and care is required when handling serum in order to preserve its functional integrity. We have previously used a whole human serum bactericidal assay to show that antibody and an intact complement ...
Colette M O'Shaughnessy   +2 more
doaj   +1 more source

Induction of bactericidal activity by degradable implants

open access: yesГений oртопедии, 2023
The development of biodegradable implants with bioactive properties is a promising direction. The purpose of this study was to evaluate the in vitro bactericidal activity of implants made from a degradable material polycaprolactone (PCL) impregnated ...
Arnold V. Popkov   +9 more
doaj   +1 more source

Fungicidal and bactericidal activity of alkyl-substituting polyetherguanidines

open access: yesБіологічні студії, 2020
Background. Polyhexamethylene guanidines are widely used as biocides and disinfectants due to the wide range of their antimicrobial activity against Gram-positive and Gram-negative bacteria, viruses, fungi, and molds.
M. Ya. Vortman   +5 more
doaj   +1 more source

Bactericidal action of photogenerated singlet oxygen from photosensitizers used in plaque disclosing agents. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Photodynamic therapy (PDT) has been suggested as an efficient clinical approach for the treatment of dental plaque in the field of dental care.
Kirika Ishiyama   +6 more
doaj   +1 more source

Harnessing a T1 Phage-Derived Spanin for Developing Phage-Based Antimicrobial Development

open access: yesBioDesign Research
The global increase in the prevalence of drug-resistant bacteria has necessitated the development of alternative treatments that do not rely on conventional antimicrobial agents.
Wakana Yamashita   +12 more
doaj   +1 more source

Bactericidal Activity of Lipid-Shelled Nitric Oxide-Loaded Microbubbles

open access: yesFrontiers in Pharmacology, 2020
The global pandemic of antibiotic resistance is an ever-burgeoning public health challenge, motivating the development of adjunct bactericidal therapies. Nitric oxide (NO) is a potent bioactive gas that induces a variety of therapeutic effects, including
Maxime Lafond   +8 more
doaj   +1 more source

In vitro bactericidal activity of 3-cinnamoyl-4-hydroxy-6-methyl-2-pyrone (CHP) against drug-susceptible, drug-resistant and drug-tolerant isolates of Mycobacterium tuberculosis

open access: yesJournal of Global Antimicrobial Resistance, 2020
Objectives: Tuberculosis (TB) poses a serious global threat to humans. New bactericidal agents that can shorten treatment duration and target drug resistance still remain a top priority in the discovery of anti-TB drugs.
Zubair Shanib Bhat   +8 more
doaj   +1 more source

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