Results 191 to 200 of about 55,271 (286)

Nano‐Encapsulated Cinnamomum cassia Essential Oil in Combination With Fluconazole Exhibits Synergistic Activity Against Fluconazole‐Resistant Nakaseomyces glabratus and Pichia kudriavzevii

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Nano‐encapsulated Cinnamomum cassia essential oil (nano‐CC‐EO) showed in vitro antifungal activity against fluconazole‐resistant Nakaseomyces glabratus and Pichia kudriavzevii clinical isolates. Checkerboard assays revealed synergistic or additive interactions between nano‐CC‐EO and fluconazole in several isolates, without evidence of antagonism. These
Mehrdad Seifi   +5 more
wiley   +1 more source

Functional Stability of Tetracycline: Practical Information for Its Use in Bacterial Selection

open access: yesAPMIS, Volume 134, Issue 5, May 2026.
ABSTRACT Genetic manipulation is widely employed in laboratories for purposes such as gene function characterization, the development of novel traits in transformed microorganisms, and the production of biotechnologically relevant compounds. A key step in this process is the selection of mutant strains, often facilitated by antibiotics.
Adrián Salazar‐Sánchez   +2 more
wiley   +1 more source

Stochastic Forces in Microbial Community Assembly: Founding Community Size Governs Divergent Ecological Trajectories

open access: yesEcology Letters, Volume 29, Issue 5, May 2026.
The processes driving community assembly are broadly categorised into deterministic and stochastic ones. With a multi‐replicated experimental design, we quantified the extent to which stochasticity at initial stages of community assembly could drive divergence into alternative ecological trajectories.
Ibuki Hayashi   +2 more
wiley   +1 more source

Integrating Physiological Rates of Thermal Stress and Repair Predicts Heat Failure During Temperature Fluctuations

open access: yesEcology Letters, Volume 29, Issue 5, May 2026.
As the frequency and intensity of extreme heat events are increasing, it is urgently important to understand how organisms respond to and recover from heat stress. Here we extend the existing Thermal Death Time framework to include the antagonistic processes of accumulation and repair of thermal injury, which operate at stressful and permissive ...
Michael Ørsted   +3 more
wiley   +1 more source

Characterisation of a cold‐adapted, thermostable glucokinase from psychrophilic Pseudoalteromonas sp. AS‐131 reveals how the enzyme achieves high thermal stability without loss of cold adaptation

open access: yesThe FEBS Journal, Volume 293, Issue 9, Page 2617-2636, May 2026.
We investigated glucokinase from the psychrophilic Pseudoalteromonas sp. AS‐131 (PsGK), which was isolated from the Antarctic Ocean. Biochemical studies revealed that PsGK is a cold‐adapted enzyme with high thermal stability, in contrast to general cold‐adapted enzymes, which have low thermal stability.
Akane Yato   +10 more
wiley   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

open access: yesThe FEBS Journal, Volume 293, Issue 9, Page 2673-2691, May 2026.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova   +5 more
wiley   +1 more source

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