Results 321 to 330 of about 355,018 (412)

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

Allergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche, Josefine Corneliussen, Kristoffer H. Johansen, Alexandre Ruiz‐Carrasco, Caroline Paulsen, Yuchen Li, Carolina Barra, Sandhya Bangaru, Monica L. Fernández‐Quintero, Ewa Bartko, Lars Blom, Esperanza Rivera‐de‐Torre   +11 more
wiley   +1 more source

Molecular Insights into Phage-Hydrogel Polymer Interactions Through Docking, Molecular Dynamics, and Machine Learning. [PDF]

Polymers (Basel)
Attar RMS, Imam MA.
europepmc   +1 more source

Isolation, characterization and control of Shiga toxin-producing Escherichia coli by using lytic bacteriophages

, 2016
ホアン, ミン ソン, HOANG, MINH SON, ホアン, ミン, ソン   +2 more
openalex   +1 more source

The effects of bacteriophage cocktail treatment on healthy gut microbiota: an <i>in vitro</i> human colon model study. [PDF]

Microb Genom
Brown TL, Ng DYK, Savva GM, Elek CKA, Docherty JAD, Cook R, Ansorge R, Telatin A, Kutter E, Adriaenssens EM.   +9 more
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Characterization of Endolysin LysG77YL from <i>Bacillus licheniformis</i>-Infecting Bacteriophage G77YL and Application as an Antimicrobial Agent. [PDF]

J Microbiol Biotechnol
Park N, Cho Y, Kang Y, Kong M.
europepmc   +1 more source

Glycolytic metabolism of CD8+ T‐cells affects susceptibility to human leukocyte antigen‐mediated abacavir‐induced hypersensitivity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida, Yuchen Sun, Noriaki Arakawa, Takuya Hirao, Tadahaya Mizuno, Shigeki Aoki, Kousei Ito, Yoshihiro Hayakawa   +7 more
wiley   +1 more source

Extract of endophytic fungus Cepalotheca foveolata (N11) inhibits lytic bacteriophage: a study on activity, cytotoxicity, and chemical profiling. [PDF]

Int Microbiol
Ullah A, Rehman TU, Khan S, Ali Q, Ali M, Haleem A, Iqbal S, Raashid M, Haq A, Ahmed S, Bogale A, Alqahtani FM, Almohammed OA.   +12 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Bacteriophage-mediated gut microbiota regulation: a bibliometric landscape analysis (2005-2024). [PDF]

Front Microbiol
Yin J, Wang H, Cui Y, Zhou X, Zhang S, Yin H.   +5 more
europepmc   +1 more source