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Bacteriophage Therapy: Developments and Directions

open access: yesAntibiotics, 2020
In an era of proliferating multidrug resistant bacterial infections that are exhausting the capacity of existing chemical antibiotics and in which the development of new antibiotics is significantly rarer, Western medicine must seek additional ...
Mikeljon P Nikolich, Andrey A Filippov
exaly   +2 more sources
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Transduction of bacteriophage Mu by bacteriophage T1

Journal of Virology, 1977
Phage T1 transduces phage Mu PFU from Mu-lysogenic donor cells to sensitive recipient cells. The efficiency of transduction depends on the chromosomal location of the Mu prophage. T1, therefore, appears to package different regions of the bacterial chromosome with different efficiencies.
M M, Bendig, H, Drexler
openaire   +2 more sources

Immunogenicity of bacteriophages

Trends in Microbiology, 2023
Hundreds of trillions of diverse bacteriophages (phages) peacefully thrive within and on the human body. However, whether and how phages influence their mammalian hosts is poorly understood. In this review, we explore current knowledge and present growing evidence that direct interactions between phages and mammalian cells often induce host ...
Kevin Champagne-Jorgensen   +3 more
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INHERITANCE IN BACTERIOPHAGE

Annals of the New York Academy of Sciences, 1952
Publisher Summary Bacteriophages are viruses that multiply exclusively inside bacterial cells. In natural environments, bacteriophages form relatively stable associations with bacteria, called lysogenic that carry the virus intracellularly, but are resistant to its lytic action.
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Bacteriophages and bacteriophage resistance

1994
Food and dairy fermentations rely on the growth and acid producing ability of the lactic acid bacteria. Many of these have remained as traditional fermentations, where the process is driven by the natural microflora associated with the raw material. Increasing consistency, improved quality and processing efficiencies have followed the development of ...
T. R. Klaenhammer, G. F. Fitzgerald
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Viruses and Bacteriophages

Science of The Total Environment, 1981
Many of the enteric viruses which are transmitted from person to person by the fecal-oral route are found in raw and treated wastewater, and because of their persistence under adverse conditions may also be found in slightly polluted waters. There is no routine examination procedure of water and wastewater for enteroviruses, mainly because of the ...
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Small Bacteriophages

1967
The chapter discusses on the various small bacteriophages. These phages are quite heterogeneous; some species contain DNA and others contain ribonucleic acid (RNA); some particles have cubic symmetry and others are made of a helical nucleoprotein structure.
Hoffman-Berling, H.   +2 more
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Packaging of genomes in bacteriophages: a comparison of ssRNA bacteriophages and dsDNA bacteriophages

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1976
Abstract In complex DNA bacteriophages like λ, T4, T7, P22, P2, the DNA is packaged into a preformed precursor particle which sometimes has a smaller size and often a shape different from that of the phage head. This packaging mechanism is different from the one suggested for the RNA phages, according to which RNA nucleates the shell ...
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Defective bacteriophages

Journal of Cellular Physiology, 1970
AbstractNaturally occurring defective phage particles, which do not form plaques on any known host, but have a restricted host killing range, appear to be widely distributed. The defective phages are produced spontaneously but can be induced, at much higher levels, by chemical and physical agents which interfere with metabolism or structure of DNA. The
A J, Garro, J, Marmur
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