Results 171 to 180 of about 190,483 (202)
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Bacteriophage T4 RegB Endoribonuclease
2001Publisher Summary The development of bacteriophage T4 is largely determined by a precisely coordinated subversion of the host RNA polymerase to permit initiation from different classes of T4-specific promoters. The synthesis, in cascade, of regulatory elements that modify the transcription apparatus, ensures the temporal ordering of the developmental
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Structure and morphogenesis of bacteriophage T4
Cellular and Molecular Life Sciences (CMLS), 2003Bacteriophage T4 is one of the most complex viruses. More than 40 different proteins form the mature virion, which consists of a protein shell encapsidating a 172-kbp double-stranded genomic DNA, a 'tail,' and fibers, attached to the distal end of the tail.
Leiman, P. G. +4 more
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Gamma-T4 hybrid bacteriophage carrying the thymidine kinase gene of bacteriophage T4
Journal of Virology, 1984Among 32 lambda-T4 recombinant phages selected for growth on a thymidylate synthetase-deficient (thyA) host, 2 were shown to carry the T4 thymidine kinase (tk) gene. The lambda-T4tk phages contain two T4 HindIII DNA fragments (2.0 and 1.5 kilobases) that hybridize to restriction fragments of T4 DNA, encompassing the tk locus at 60 kilobases on the T4 ...
A J, Mileham, N E, Murray, H R, Revel
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On the Structure of the Scaffolding Core of Bacteriophage T4
Journal of Computational Biology, 1999The scaffolding core in bacteriophages is a temporary structure that plays a major role in determining the shape of the protein shell that encapsulates the viral DNA. In the currently accepted structure for the scaffolding core in bacteriophage T4, there is a symmetry mismatch between the protein shell, which has fivefold symmetry, and the scaffolding ...
Bonnie Berger +3 more
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Assembly of the tau of bacteriophage T4
Journal of Molecular Biology, 1968Abstract The formation of bacteriophage T4 has been studied by characterizing the phage components accumulating in cells infected—under restrictive conditions—with mutants blocked at different stages of the assembly process. Three structures which appear to be intermediates in tail assembly have been isolated by centrifugation: baseplates (S20,w ≅ 80
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On the regulation of the morphogenesis of bacteriophage T4
Journal of Molecular Biology, 1963Two steps in the morphogenesis of bacteriophage T4 were studied; the formation of the “early” proteins and of phage structural elements. The synthesis of the “late” phage proteins was prevented if the “early” proteins were defective (containing 7-azatryptophan or p -fluorophenylalanine).
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Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era
Acta Pharmaceutica Sinica B, 2022Jin Sun, Zhonggui He, Qiuhua Luo
exaly
Lambda and T4 bacteriophage hybrids
Journal of Molecular Biology, 1977L P, Tikhomirova +3 more
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The structure of the “Polyheads” of T4 bacteriophage
Journal of Molecular Biology, 1964J T, FINCH, A, KLUG, A O, STRETTON
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