Results 201 to 210 of about 14,881 (257)

Rectal Colonization by Carbapenemase-Producing Enterobacterales in a Tertiary Care Hospital in Havana, Cuba. [PDF]

Antibiotics (Basel)
Yu H, Carmona Y, Bouza V, González MK, Torres GE, Rodríguez VR, González AH, Kobayashi N, Aung MS, Ruiz-Garbajosa P, Cantón R, Pérez DQ.   +11 more
europepmc   +1 more source

Integrated Engineering of CAR‐T Cells for Solid Tumours

Cell Proliferation, EarlyView.
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang, Tan Li, Ping He, Zhijie Zhao, Shenglong Li, Liming Wang   +5 more
wiley   +1 more source

Multidrug-resistant <i>Klebsiella pneumoniae</i> in a pediatric ICU: Emergence of newly identified ST7120 and the first report of ST792 in Taiwan. [PDF]

New Microbes New Infect
Chen YC, Kao CY, Chen CC, Tang HJ, Chang TH.   +4 more
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

A guide to the ecological limitations of phage therapy of bacterial biofilms: Is what's best for the phage best for the physician?

The FEBS Journal, EarlyView.
Bacteriophages—viruses that kill bacteria—are promising weapons against bacterial biofilms: sessile communities notoriously resistant to antibiotics. Yet phages evolved not so much to eradicate bacteria as to obtain new bacteria to infect. That goal, however, may conflict with the physician's objective of complete bacterial clearance.
Stephen T. Abedon
wiley   +1 more source

Epidemiological and Genomic Characteristics of <i>bla</i> _CTX-M and <i>bla</i> _NDM-Producing <i>K. pneumoniae</i> From Dairy Cows in Henan Province, China. [PDF]

Transbound Emerg Dis
Feng Y, Li W, Ma M, Zhai Y, Wu H, Liu J, Hu G, He D, Pan Y.   +8 more
europepmc   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Klebsiella pneumoniae Carbapenemase-Producing Enterobacterales Infection and Colonization in a Long-Term Care Facility - Ontario, Canada, May 2024-January 2025. [PDF]

MMWR Morb Mortal Wkly Rep
Aloosh M, Saeed HM, Mataseje LF.
europepmc   +1 more source

Innovative Field Applications of Probiotics, Prebiotics, and Medicinal Plant Products for Disease Control in Aquaculture

Journal of Fish Diseases, EarlyView.
ABSTRACT Disease outbreaks and the associated reliance on antibiotics pose major constraints to the sustainability of modern aquaculture. As regulatory pressures increase and consumer demand shifts toward residue‐free production, diverse biological interventions are gaining prominence as viable alternatives to chemotherapeutics.
Mustafa Öz, Enes Üstüner, Sümmani Çifci, Suat Dikel, Emin İleri, Furkan Budak   +5 more
wiley   +1 more source

Genome-wide approaches to bacterial strain typing: a history and review of recent methodological advances. [PDF]

Curr Opin Infect Dis
Shropshire WC, Hanson BM, Shelburne SA.
europepmc   +1 more source