Results 241 to 250 of about 15,223 (299)

Writing Big in Plant Genomes: Advances, Challenges and Strategies for Targeted Large‐Fragment DNA Insertion

Plant, Cell &Environment, EarlyView.
ABSTRACT Precise genome editing has transformed plant biology and crop improvement by enabling targeted modification of endogenous loci. Beyond gene knockout and base editing, the site‐specific insertion of exogenous DNA, particularly large DNA fragments, has become a central goal for engineering complex traits, reconstructing metabolic pathways and ...
Fengfeng Zhang, Daqi Yan, Jiayi Hou, Dan Yang, Yan Xiong, Mingzhang Wen, Xiaoyue Zhu   +6 more
wiley   +1 more source

The effects of far‐UVC irradiation on the presence and concentration of ESKAPEE pathogens on hospital surfaces: Study protocol for a multi‐site, double‐blinded randomized controlled trial in La Paz, Bolivia

Photochemistry and Photobiology, EarlyView.
The protocol of a multi‐site, double‐blinded, clustered randomized controlled trial (cRCT) with a binary outcome of the presence of viable presumptive ESKAPEE pathogens on surfaces in and around hospital sinks is to be implemented in two Bolivian hospitals.
Lindsay B. Saber, Melani Rojas, Darcy M. Anderson, Deverick J. Anderson, Holger Claus, Ryan Cronk, Karl G. Linden, Megan E. J. Lott, Lewis J. Radonovich Jr., Bobby G. Warren, Richard D. Williamson, Richard L. Vincent, Sergio Gutiérrez‐Cortez, Carla Calderón Toledo, Joe Brown   +14 more
wiley   +1 more source

Rectal Colonization by Carbapenemase-Producing Enterobacterales in a Tertiary Care Hospital in Havana, Cuba. [PDF]

Antibiotics (Basel)
Yu H, Carmona Y, Bouza V, González MK, Torres GE, Rodríguez VR, González AH, Kobayashi N, Aung MS, Ruiz-Garbajosa P, Cantón R, Pérez DQ.   +11 more
europepmc   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Pan-genomic insights into resistance, virulence, and stress adaptation in <i>Clostridium perfringens</i> from the Tibetan Plateau. [PDF]

mSphere
Luo R, Wan Y, Chen W, Wei H, Wang J, Bai Z, Li K, Zhong Y, Ma B, Jin H, Suolang S.   +10 more
europepmc   +1 more source

Bacterial screening of platelet donations in England, 2014–2023

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Bacterial contamination of blood components is an ongoing problem in transfusion medicine. We analysed the bacterial screening data of platelets from England, 2014–2023, and compared this with data on reported near‐misses and transfusion‐transmitted infections (TTIs). Materials and Methods Anonymized data on bacterial
Vidushi Chugh, Shannah Secret, Katy Davison, Autumn St John, Peter Simmonds, Susan R. Brailsford, Heli Harvala   +6 more
wiley   +1 more source

Epidemiological and Genomic Characteristics of <i>bla</i> _CTX-M and <i>bla</i> _NDM-Producing <i>K. pneumoniae</i> From Dairy Cows in Henan Province, China. [PDF]

Transbound Emerg Dis
Feng Y, Li W, Ma M, Zhai Y, Wu H, Liu J, Hu G, He D, Pan Y.   +8 more
europepmc   +1 more source

International multicentre evaluation of a new anti‐idiotypic anti‐daratumumab for resolving pre‐transfusion interferences

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Daratumumab, a therapeutic human anti‐CD38 monoclonal antibody, improves multiple myeloma outcomes but interferes with pre‐transfusion testing by binding CD38 on reagent red blood cells (RBCs), potentially masking clinically significant alloantibodies.
Arnaud Reggiani, Sofia Lejon Crottet, Sophie Waldvogel, Charlotte Engström, Serelina Coluzzi, Antonella Matteocci, Janis R. Hamilton, Levent Tufan Kumas, Karen M. K. de Vooght, Jill R. Storry, Jennylyn Flores, Núria Nogués, Carlos Cotorruelo, Molly Rutherford, Eveline B. Nilsen, Monika Pelc‐Kłopotowska, Jolanta Korzeniowska, Alessandra Baffa, Inna Sareneva, Nor Hafizah Ahmad, Katarzyna Szczudlo, Athif Rahman, Laser Sanal, Lise Jørgensen, Karolina Majewska Rochowiak, Monika Salwierz, Elisaveta Grancharova, Bojana Zivkovic, Jessica Alvarez, Mareike Riedl, Achim Knappik   +30 more
wiley   +1 more source

Klebsiella pneumoniae Carbapenemase-Producing Enterobacterales Infection and Colonization in a Long-Term Care Facility - Ontario, Canada, May 2024-January 2025. [PDF]

MMWR Morb Mortal Wkly Rep
Aloosh M, Saeed HM, Mataseje LF.
europepmc   +1 more source

Nanopore sequencing enables highly accurate genotyping and identification of resistance determinants in key nosocomial pathogens. [PDF]

Microb Genom
Cottingham H, Judd LM, Harshegyi-Hand T, Wisniewski JA, Blakeway LV, Hong T, Parker MH, Peleg AY, Holt KE, Hawkey J, Macesic N.   +10 more
europepmc   +1 more source