Results 321 to 330 of about 11,802,102 (404)

Assessment of Patients With Beta‐Lactams Positive Provocation Tests by Biomarkers of IgG‐Related Neutrophil Activation

open access: yesClinical &Experimental Allergy, EarlyView.
Neutrophil activation in beta‐lactams (BL) immediate hypersensitivity reactions (IHR). Factor component analysis of IHR biomarkers suggests an IgG‐mediated mechanism. We propose Neutrophil Elastase as a biomarker of neutrophil activation in BL IHR. ABSTRACT Background Beta‐lactams (BLs) are the predominant cause of immediate allergic reactions to drugs.
Adrienne Astrid Gallizzi   +13 more
wiley   +1 more source

Genomic analysis and therapeutic efficacy evaluation of bacteriophage PK2420 for pneumonia caused by hypervirulent <i>Klebsiella pneumoniae</i> (K20 serotype). [PDF]

open access: yesmSystems
Chen J   +24 more
europepmc   +1 more source

Prime Editing: A Revolutionary Technology for Precise Treatment of Genetic Disorders

open access: yesCell Proliferation, Volume 58, Issue 4, April 2025.
This review outlines the latest research advancements in prime editing technology, delivery strategies, and the challenges that must be addressed to fully realize its therapeutic potential, emphasizing the high potential of prime editing in the remission or cure of genetic diseases. ABSTRACT Genetic diseases have long posed significant challenges, with
Mengyao Li, Yi Lin, Qiang Cheng, Tuo Wei
wiley   +1 more source

Simultaneous Discovery–Invention in Corporate R&D: Lessons from the CRISPR Case

open access: yesEuropean Management Review, EarlyView.
Abstract Some companies invest in fundamental research, but many struggle when developing novel in‐house scientific knowledge and integrating it into their new inventions. While the literature advocates revised approaches to better understand this phenomenon, we investigate the processes that lead to Simultaneous Discovery–Invention (SDI).
Quentin Plantec   +2 more
wiley   +1 more source

Hybrid strains of enterotoxigenic/Shiga toxin-producing <i>Escherichia coli</i>, United Kingdom, 2014-2023. [PDF]

open access: yesJ Med Microbiol
Rodwell EV   +6 more
europepmc   +1 more source

Review of Pseudomonas aeruginosa and Klebsiella pneumoniae as venereal pathogens in horses

open access: yesEquine Veterinary Journal, Volume 57, Issue 3, Page 587-597, May 2025.
Abstract Three bacteria extensively acknowledged as venereal pathogens with the potential to induce endometritis include Taylorella equigenitalis, the causative agent of contagious equine metritis (CEM), specific strains of Pseudomonas aeruginosa, and certain capsule types of Klebsiella pneumoniae.
Melanie Scholtz   +3 more
wiley   +1 more source

Reversible excision of thewzylocus inSalmonellaTyphimurium may aid recovery following phage predation

open access: yes
Charity OJ   +7 more
europepmc   +1 more source

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