Results 271 to 280 of about 129,818 (339)

Bacteriophages as a modern diagnostic tool: innovations, applications and challenges. [PDF]

open access: yesMol Biol Rep
Olszewska P   +4 more
europepmc   +1 more source

B‐Cell Repertoire of Children With Atopic Dermatitis Exhibits Altered IgE Maturation Associated With Allergic Food Sensitization

open access: yesAllergy, EarlyView.
IgH repertoire sequencing of a large atopic dermatitis cohort reveal reduced IgE somatic hypermutation and increased IgE diversity associated with food allergen sensitization. Presence of a dog during the first year of life is associated with increased IgE somatic hypermutation, possibly countering the effect of food sensitization.
Kirandeep K. Gill   +18 more
wiley   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz   +8 more
wiley   +1 more source

Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos

open access: yesCell Proliferation, EarlyView.
Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang   +10 more
wiley   +1 more source

Complete genome sequence of <i>Pseudomonas aeruginosa</i> bacteriophage PaFZ4 isolated from Dhaka, Bangladesh. [PDF]

open access: yesMicrobiol Resour Announc
Mahtab Z   +6 more
europepmc   +1 more source

A Review of Phage Therapy for Aquaculture Applications: Efficacy, Health Ramifications and Research Challenges

open access: yesFish and Fisheries, EarlyView.
Bacteriophage therapy is characterised by numerous advantages, facilitating its diverse aquaculture application and efficacy as an antibiotic alternative mitigating the spread of antimicrobial‐resistant pathogens. Contributing to the modern reappraisal of the aquaculture application of bacteriophage therapy, challenges impeding its widespread ...
Louise James   +4 more
wiley   +1 more source

The potential novel bacteriophages against multidrug-resistant Edwardsiella tarda isolates from striped catfish Pangasianodon hypophthalmus. [PDF]

open access: yesSci Rep
Ho TT   +14 more
europepmc   +1 more source

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