Results 291 to 300 of about 129,818 (339)

Investigating the molecular mechanisms underlying the anti‐CRISPR function of AcrIIA13b protein

The FEBS Journal, EarlyView.
Anti‐CRISPR protein AcrIIA13b inhibits CRISPR–Cas9 function by preventing target DNA engagement. The Cas9–sgRNA ribonucleoprotein (RNP) normally recognizes the protospacer adjacent motif (PAM) duplex to initiate DNA cleavage. AcrIIA13b binding to the PAM‐interacting WED–PI domain blocks this recognition, leaving the target DNA intact.
So Yeon Lee, Hyun Ho Park
wiley   +1 more source

Isolation and genomic analysis of seven phages active against carbapenem-resistant <i>Klebsiella pneumoniae</i>. [PDF]

Microbiol Resour Announc
Cuello L, Parmar K, Supandy A, Van Tyne D, Patel R.   +4 more
europepmc   +1 more source

Viability and preservation of the lytic spectra of Salmonella bacteriophages during storage

, 2007
Elisabete Fernandes, Lara Raquel Pinto Amorim, Ana Nicolau, Joana Silva, Joana Azeredo, Paula Teixeira   +5 more
openalex   +1 more source

Plant‐produced encapsulin displays non‐typhoidal Salmonella enterica antigens and assembles into mosaic nanoparticles

The FEBS Journal, EarlyView.
This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Justin B. Renaud, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +6 more
wiley   +1 more source

Complete genome sequences of four <i>Phikmvirus</i> bacteriophages from Kenyan sewage lytic against multidrug-resistant <i>Pseudomonas aeruginosa</i>. [PDF]

Microbiol Resour Announc
Omwega MT, Gachoya M, Georges M, Kigen C, Wachira J, Natasha V, Nikolich MP, Kamanyi K, Nyamweya S, Odoyo E, Musila L.   +10 more
europepmc   +1 more source

Endonuclease restriction analyses and transduction analyses on bacteriophages of the plant pathogen Pseudomonas syringae

, 2011
Russell O. Nordeen
openalex   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source

Bacteriophage Therapy: Overcoming Antimicrobial Resistance Through Advanced Delivery Methods. [PDF]

Molecules
Wacnik M, Hauza E, Skaradzińska A, Śliwka P.   +3 more
europepmc   +1 more source

Potential of Nitric Oxide and Bacteriophages as Combined Antibacterial Agents to Counter Drug-Resistant Infections. [PDF]

ACS Appl Bio Mater
Wilson SN, Gondil VS, Brisbois EJ, Handa H.   +3 more
europepmc   +1 more source