Results 231 to 240 of about 147,965 (298)

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Gut Microbiome Dysbiosis Promotes Gallstone Formation via Bile Acid Metabolic Disorder: A Multiomics Study. [PDF]

FASEB J
Huang C, Xiao W, Zhao J, Zhong R, Gao L, Ma H, Tian L, Yue P, Lin Y, He Q, Xia B, Yuan J, Yang M, Meng W.   +13 more
europepmc   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1309-1325, May 2026.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

Gut Microbiota Alterations in Hypothyroidism: A Pilot Study Revealing Increased Abundance of Specific Bacterial Genera. [PDF]

J Nutr Metab
Tavassol ZH, Farsi F, Ettehad-Marvasti F, Ejtahed HS, Hasani-Ranjbar S.   +4 more
europepmc   +1 more source

Application of Metagenomic Next‐Generation Sequencing in the Diagnosis of Pneumonia in Patients With Cancer

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background With the development of new sequencing technologies, metagenomic next‐generation sequencing (mNGS) has become a diagnostic tool for respiratory tract infections. Patients with cancer may develop pneumonia caused by infections or antitumor therapy.
Rong Qin, Chao Wang, Minghua Cong, Le Tian, Ning Li   +4 more
wiley   +1 more source

The effect of gestational weight gain on the infant gut microbiome- a systematic review of the literature. [PDF]

Front Cell Infect Microbiol
Xixi NA, Karamanolis G, Vlachogianni EE, Voulgaris T, Sokou R, Volaki P, Paliatsiou S, Iliodromiti Z, Iacovidou N, Boutsikou T.   +9 more
europepmc   +1 more source

Parvimonas micra promotes carcinogenesis of colorectal cancer through phenyllactic acid‐induced DNA damage

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Multiomics analysis of the faecal samples from CRC patients found that upregulation of P. micra and PLA was associated with the CRC development. PLA from P. micra via pdhD genes could induce DNA damage via AHR signalling pathway to mediate carcinogenesis.
Shuang Guo, Mujia Cao, Jinjie Wu, Wenhao Ma, Dayi Liang, Hongyu Xie, Yanchun Xie, Zhanhao Luo, Peng Lai, Danling Liu, Wanyi Zeng, Jingbiao Zheng, Mengze Xing, Xiqi Yin, Min Xia, Zhen He   +15 more
wiley   +1 more source

Modulation of the gut-heart axis by exercise in diabetic cardiomyopathy: Microbial mechanisms and clinical implications. [PDF]

iScience
Chen J, Fan Z, Li Y, Duan R, Gao B.
europepmc   +1 more source

Intersecting Molecular Pathways in Cardiovascular Disease and Diabetes Mellitus: Emerging Roles of Inflammation and Therapeutics

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 4, May 2026.
Central illustration: Pathophysiological mechanisms linking diabetes mellitus and cardiovascular disease. Chronic hyperglycaemia, insulin resistance, and low‐grade inflammation contribute to endothelial dysfunction, myocardial fibrosis, and cardiomyocyte apoptosis.
Lilian Anagnostopoulou, Nikolaos Ktenopoulos, Anastasios Apostolos, Christos Fragoulis, Panayotis Vlachakis, Paschalis Karakasis, Marios Sagris, Nikias Milaras, Maria Drakopoulou, Andreas Synetos, Ioannis Kyriazis, Ioannis Ioannidis, Costas Tsioufis, Konstantinos Toutouzas   +13 more
wiley   +1 more source