Results 171 to 180 of about 72,511 (320)

Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis

open access: yesNature Network Boston, 2016
Bacteroides fragilis is the leading cause of anaerobic bacteremia and sepsis. Enterotoxigenic strains that produce B. fragilis toxin (BFT, fragilysin) contribute to colitis and intestinal malignancy, yet are also isolated in bloodstream infection.
Vivian M. Choi   +6 more
semanticscholar   +1 more source

Improvement of the Anticancer Efficacy of PD‐1/PD‐L1 Blockade: Advances in Molecular Mechanisms and Therapeutic Strategies

open access: yesMedComm, Volume 6, Issue 8, August 2025.
Mechanisms of alleviating resistance to PD‐1/PD‐L1 blockade by IFN‐α and IFN‐β. In these mechanisms, the “yin‐yang balance” is disrupted, thus preventing T cells from attacking cancer cells. Restoring this balance may improve the efficacy of anti‐PD‐1/PD‐L1 therapy and reinvigorate T cells and other immune cells to target and destroy cancer cells ...
Peng Gao   +7 more
wiley   +1 more source

Tryptic Soy Bile-Kanamycin Test for the Identification of Bacteroides fragilis [PDF]

open access: gold, 1974
Valerie Vargo   +2 more
openalex   +1 more source

Gut microbiome compositional and functional features associate with Alzheimer's disease pathology

open access: yesAlzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract BACKGROUND The gut microbiome is a potentially modifiable risk factor for Alzheimer's disease (AD); however, understanding of its composition and function regarding AD pathology is limited. METHODS Shallow‐shotgun metagenomics was used to analyze the fecal microbiome of participants in the Wisconsin Microbiome in Alzheimer's Risk Study ...
Jea Woo Kang   +22 more
wiley   +1 more source

Influence of Citrobacter freundii on NINJ2 Expression and Oxaliplatin Resistance in Colorectal Cancer

open access: yesCancer Medicine, Volume 14, Issue 13, July 2025.
Oxaliplatin resistance was found to be induced in colon cancer cells by bacterial filtrates from Citrobacter freundii. This resistance was associated with downregulation of the NINJ2 gene, which was found to suppress apoptosis and reactive oxygen species.
Reio Ueta   +5 more
wiley   +1 more source

Microplastics and the Rising Tide of Early‐Onset Colorectal Cancer: Exploring the Environmental Gut Connection

open access: yes
ANZ Journal of Surgery, EarlyView.
Rathin Gosavi   +5 more
wiley   +1 more source

Cancer stem cells: Bridging microenvironmental interactions and clinical therapy

open access: yesClinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Cancer stem cells (CSCs) drive tumor progression through their dynamic self‐renewal capacity, epigenetic plasticity, and drug resistance. These cells interact bi‐directionally with the tumor ecosystem to promote immunosuppressive reprogramming and metastatic spread.
Huiling Wang   +3 more
wiley   +1 more source

The Comparison of the Gut Microbiome Composition, Serum Inflammatory Markers and Faecal Short‐Chain Fatty Acids Among Individuals With Type 1 and 2 Diabetes Mellitus With Healthy Controls: A Case–Control Study

open access: yesEndocrinology, Diabetes &Metabolism, Volume 8, Issue 4, July 2025.
Gut microbiome, inflammation and short‐chain fatty acids in type 1 and type 2 diabetes. ABSTRACT Background This study aimed to compare the gut microbiome (GM) composition, serum inflammatory markers and faecal short‐chain fatty acids among individuals with type 1 and type 2 diabetes mellitus (DM) and healthy controls.
Hossein Yarmohammadi   +11 more
wiley   +1 more source

A highly conserved SusCD transporter determines the import and species-specific antagonism of Bacteroides ubiquitin homologues

open access: yesNature Communications
Efficient interbacterial competitions and diverse defensive strategies employed by various bacteria play a crucial role in acquiring a hold within a dense microbial community.
Ming Tong   +13 more
doaj   +1 more source

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