Results 1 to 10 of about 147,965 (298)

Microbiome‐Based Clustering Identifies Glycemic Control‐Related Subtypes in Youth With Recent‐Onset Type 1 Diabetes [PDF]

MedComm
Type 1 diabetes (T1D) in children exhibits substantial heterogeneity in glycemic control, yet the biological mechanisms underlying this variation remain unclear. We aimed to explore endotype heterogeneity in youth with recent‐onset T1D using unsupervised
Huiling Tan, Yu Ding, Zhaohe Gu, Xulin Wang, Jing Wang, Tian Wei, Xiaoya Zhang, Lanxin Pan, Yu Shi, Shiru Chang, Chuang Guo, Jianping Weng, Xueying Zheng, Tong Yue   +13 more
doaj   +2 more sources

Differences in the Biliary Microbiome Between Biliary Tract Cancer and Benign Biliary Disease [PDF]

Microorganisms
Bile contains many bacteria that can contribute to various diseases. Therefore, identifying bile microbiome differences between benign and malignant conditions is essential.
Hye Ji Lee, Sung Hee Park, Sung Yong Han, Jong Hyun Lee, Dong Uk Kim, Hyung Il Seo   +5 more
doaj   +2 more sources

Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in Bacteroides thetaiotaomicron [PDF]

Journal of Bacteriology
Bacteroides spp. are gram-negative, gut commensals that shape the enteric landscape by producing outer membrane vesicles (OMVs) that degrade dietary fibers and traffic immunomodulatory biomolecules.
Evan J. Pardue, Tengfei Zhong, Nichollas E. Scott, Biswanath Jana, Wandy Beatty, Juan C. Ortiz-Marquez, Mohammed Kaplan, Clay Jackson-Litteken, Mario F. Feldman   +8 more
doaj   +2 more sources

Activation of a Specific Gut Bacteroides-Folate-Liver Axis Benefits for the Alleviation of Nonalcoholic Hepatic Steatosis

Cell Reports, 2020
Summary: A beneficial gut Bacteroides-folate-liver pathway regulating lipid metabolism is demonstrated. Oral administration of a Ganoderma meroterpene derivative (GMD) ameliorates nonalcoholic hepatic steatosis in the liver of fa/fa rats by reducing ...
Kai Wang, Nan Zhou, Ke Ma
exaly   +3 more sources

Can prebiotics help tackle the childhood obesity epidemic?

Frontiers in Endocrinology, 2023
Globally, excess weight during childhood and adolescence has become a public health crisis with limited treatment options. Emerging evidence suggesting the involvement of gut microbial dysbiosis in obesity instills hope that targeting the gut microbiota ...
Yaqin Wang, Yaqin Wang, Anne Salonen, Ching Jian, Ching Jian   +4 more
doaj   +1 more source

The composition of the gut microbiome in patients with sarcopenia

Türk Biyokimya Dergisi, 2022
The purpose of this study is to predict sarcopenia by analyzing the composition of the gut microbiota.
Wu Yue, Xia Yanting, Huang Shunmei, Liu Shiyu, Yang Ji, Yang Yunmei, Zhu Xuan   +6 more
doaj   +1 more source

Nutrient niche specificity for glycosaminoglycans is reflected in polysaccharide utilization locus architecture of gut Bacteroides species

Frontiers in Microbiology, 2022
IntroductionGlycosaminoglycans (GAGs) present in the mucosal layer can be used as nutrients by certain intestinal bacteria, particularly members of the Bacteroides.
Annelieke Overbeeke, Annelieke Overbeeke, Bela Hausmann, Bela Hausmann, Georgi Nikolov, Fatima C. Pereira, Craig W. Herbold, David Berry, David Berry   +8 more
doaj   +1 more source

Salmonella-induced changes in the level of key immunoregulatory bacteria affect the transcriptional activity of the Foxp3 and RORgt genes in the gut-associated lymphoid tissue of rats

Инфекция и иммунитет, 2020
Intestinal microbes involved in many physiological processes owner, contributes to the formation and maintenance of immune homeostasis by regulating immune responses to protect against colonization by pathogens.
Yu. V. Bukina, L. Ya. Fedoniuk, G. D. Koval, Yu. O. Shekhovtsova, A. M. Kamyshnyi, A. O. Gubar, V. O. Gubka   +6 more
doaj   +1 more source

Cesarean section induced dysbiosis promotes type 2 immunity but not oxazolone-induced dermatitis in mice

Gut Microbes, 2023
Delivery by cesarean section (CS) is associated with an altered gut microbiota (GM) colonization and a higher risk of later chronic inflammatory diseases.
Line Fisker Zachariassen, Maria Bernadette Bergh Ebert, Caroline Märta Junker Mentzel, Ling Deng, Lukasz Krych, Dennis Sandris Nielsen, Jakob Stokholm, Camilla Hartmann Friis Hansen   +7 more
doaj   +1 more source

Identifying Keystone Species in the Human Gut Microbiome from Metagenomic Timeseries using Sparse Linear Regression [PDF]

, 2014
Human associated microbial communities exert tremendous influence over human health and disease. With modern metagenomic sequencing methods it is possible to follow the relative abundance of microbes in a community over time.
Fisher, Charles K., Mehta, Pankaj
core   +9 more sources